ReviewJournal of biomechanical engineering2015
Multiscale contribution of bone tissue material property heterogeneity to trabecular bone mechanical behavior.
Review in Journal of biomechanical engineering, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Article
- Longitudinal and radial microgradients in porosity and canal diameter in femur bone and its implications for bone regeneration and bone repair implants.Frontiers in bioengineering and biotechnology · 2026Article
- Heterogeneous material models for finite element analysis of the human mandible bone - A systematic review.Heliyon · 2024Review
- A pilot study on the nanoscale properties of bone tissue near lacunae in fracturing women.Bone reports · 2022Article
- Matrix/mineral ratio and domain size variation with bone tissue age: A photothermal infrared study.Journal of structural biology · 2022Article
- The BALB/c mouse as a preclinical model of the age-related deterioration in the lumbar vertebra.Bone · 2020Article
- Microstructure, mineral and mechanical properties of teleost intermuscular bones.Journal of biomechanics · 2019Article
- Cathepsin K inhibition preserves compressive load in lumbar vertebrae of osteoporotic monkeys.Bone reports · 2018Article
- Dynamic structure and composition of bone investigated by nanoscale infrared spectroscopy.PloS one · 2018Article
- Applying Full Spectrum Analysis to a Raman Spectroscopic Assessment of Fracture Toughness of Human Cortical Bone.Applied spectroscopy · 2017Article
- Article
- Microscopy techniques for investigating the control of organic constituents on biomineralization.MRS bulletin · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Heterogeneity of material properties is an important potential contributor to bone fracture resistance because of its putative contribution to toughness, but establishing the contribution of heterogeneity to fracture risk is still in an incipient stage. Experimental studies have demonstrated changes in distributions of compositional and nanomechanical properties with fragility fracture history, disease, and pharmacologic treatment. Computational studies have demonstrated that models with heterogeneous material properties predict apparent stiffness moderately better than homogeneous models and show greater energy dissipation. Collectively, these results suggest that microscale material heterogeneity affects not only microscale mechanics but also structural performance at larger length scales.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.