Evidence map›Paper›PMID 25383256›Full record

ArticleCurrent nutrition reports2014

Prevention of Diabetes Through the Lifestyle Intervention: Lessons Learned from the Diabetes Prevention Program and Outcomes Study and its Translation to Practice.

Mary A Hoskin, George A Bray, Kathy Hattaway, Prajakta A Khare-Ranade, Jeremy Pomeroy, Linda N Semler, Valarie A Weinzierl, Judith Wylie-Rosett, for the Diabetes Prevention Program Research Group

Abstract read
In one paragraph

Article in Current nutrition reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Review
  8. Prediabetes.Nature reviews. Disease primers · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Prevention in Prison: The Diabetes Prevention Program in a Correctional Setting.Diabetes spectrum : a publication of the American Diabetes Association · 2019
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mary A HoskinACKCO, American Indian Professional Services, Inc. Phoenix, AZ.
George A BrayPennington Biomedical Center, Louisiana State University, Baton Rouge, LA.
Kathy HattawayUniversity of Texas, San Antonio, TX.
Prajakta A Khare-RanadeWashington University, St Louis, MO.
Jeremy PomeroyPhoenix Epidemiology and Clinical Research Branch, NIDDK Phoenix, AZ.
Linda N SemlerUniversity of Pittsburgh, Pittsburgh, PA.
Valarie A WeinzierlUniversity of Pittsburgh, Pittsburgh, PA.
Judith Wylie-RosettAlbert Einstein College of Medicine, Bronx, NY.
for the Diabetes Prevention Program Research Group

Funding

PRIMARY PREVENTION TRIAL--DATA COORDINATING CENTERU01DK048489 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI JABLONSKI, KATHLEEN ANN, TEMPROSA, MARINELLA · 1994 to 2021
$84.8M
Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Sakeneh Zraika · 1986 to 2026
$41.4M
NIDDK NIH HHS P30 DK017047NIDDK NIH HHS U01 DK048489
6 · The paper itself

Abstract

A number of strategies have been used to delay or prevent the development of type 2 diabetes mellitus (T2D) in high-risk adults. Among them were diet, exercise, medications and surgery. This report focuses on the nutritional lessons learned from implementation of the Intensive Lifestyle Intervention (ILI) in the DPP and its follow-up DPPOS that looked at weight loss through modification of diet and exercise. The Diabetes Prevention Program (DPP) is a large clinical trial, sponsored by the National Institutes of Health, designed to look at several strategies to prevent conversion to type 2 diabetes (T2D) by adults with prediabetes (IGT/IFG) including an Intensive Lifestyle Intervention (ILI). The ∼3800 ethnically diverse participants (46% reported non-white race) were overweight, had impaired glucose tolerance (IGT) and impaired fasting glucose (IFG). Treatments were assigned randomly. The Diabetes Prevention Program Outcomes Study (DPPOS) is a follow up study evaluating the long-term outcomes of the clinical trial.

Indexed as

diabetesDiabetes preventiondietgeneticslifestyleLifestyle interventionnutritionoverweightphysical activitypreventiontype 2 diabetesweight loss

Identifiers

PMID25383256
PMCPMC4221569

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.