ArticleJournal of clinical hypertension (Greenwich, Conn.)2015
Association of hyperuricemia with conventional cardiovascular risk factors in elderly patients.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 21 citations in OpenAlex.
- The Effects of Pharmacological Urate-Lowering Therapy on Cardiovascular Disease in Older Adults with Gout.Drugs & aging · 2024Review
- One-Year Risk Prediction of Elevated Serum Uric Acid Levels in Older Adults: A Longitudinal Cohort Study.Clinical interventions in aging · 2024Article
- Risk Factors and Cardiovascular Disease in the Elderly.Reviews in cardiovascular medicine · 2022Review
- Article
- [Correlations of echocardiographic parameters in Gout patients: a retrospective analysis].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020Article
- Roles of hyperuricemia in metabolic syndrome and cardiac-kidney-vascular system diseases.American journal of translational research · 2018Review
- Uric acid in the pathogenesis of metabolic, renal, and cardiovascular diseases: A review.Journal of advanced research · 2017Review
- Evaluation of patients diagnosed with essential arterial hypertension through network analysis.Irish journal of medical science · 2016Observational
- Reply to "Association of Serum Uric Acid Concentration With Metabolic Risk Factors in Patients With Type 2 Diabetes".Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
- Association of Serum Uric Acid Concentration With Metabolic Risk Factors in Patients With Type 2 Diabetes.Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
- Beauty in Simplicity: Abnormal Neutrophil to Lymphocyte Ratio in Resistant Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between serum uric acid (UA) and cardiovascular risk profile was investigated in 557 outpatients (415 women) aged 60 years and older. Patients were grouped according to a UA cutoff level of 5.5 mg/dL. Prevalence of obesity, hypertension, and impaired glucose metabolism was increased in women with higher UA, who had higher body mass index (37.7±6.9 vs 33.1±5.9 kg/m(2) , P<.001), waist circumference, and serum glucose and triglyceride concentrations than women with lower UA levels. Conversely, men with higher UA levels showed lower high-density lipoprotein cholesterol and higher left ventricular mass than men with lower UA levels. Estimated glomerular filtration rate was reduced in patients with high UA levels of both sexes (65±17 vs 72±16 mL/min/1.73 m(2) , P<.001, for women; 70±16 vs 76±15 mL/min/1.73 m(2) , P<.03, for men). Grouping patients by sex-specific median UA concentrations produced similar results. These data indicate that, even in the elderly, UA clusters in a sex-specific fashion with features of metabolic syndrome and signs of target organ damage.
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