Evidence map›Paper›PMID 25381766›Full record

ArticleThe Journal of investigative dermatology2014

Psoriasis and the MAITing game: a role for IL-17A+ invariant TCR CD8+ T cells in psoriasis?

Andrew Johnston, Johann E Gudjonsson

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of investigative dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew JohnstonDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: andjoh@med.umich.edu.
Johann E GudjonssonDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
University of Michigan · US

Funding

Role of the Psoriasis Associated IL23R Risk Variants on Th17 Biology and FunctionK08AR060802 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GUDJONSSON, JOHANN ELI · 2011 to 2015
$636k
Biologic Activities of IL-36 Cytokines in PsoriasisK01AR064765 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JOHNSTON, ANDREW · 2013 to 2017
$506k
NIAMS NIH HHS K01 AR064765NIAMS NIH HHS K08 AR060802
6 · The paper itself

Abstract

Recent findings have indicated that the majority of IL-17A+ CD8+ T cells in the blood belong to a subset of innate T cells named mucosa-associated invariant T cells (MAITs). In this issue, Teunissen and colleagues (2014) demonstrate that, although MAIT cells are found in psoriatic skin, they are not increased in abundance and that the majority of IL-17A+CD8+ T cells in plaques of psoriasis are devoid of MAIT cell characteristics.

Indexed as

CD8-Positive T-LymphocytesFemaleHumansInterleukin-17MalePsoriasisSkinT-LymphocytesInterleukin-17

Identifiers

PMID25381766
PMCPMC4228793
OpenAlexW2032134572

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.