ReviewMolecular neurobiology2015
Is Cytoplasmic PTEN a Specific Target for Neuronal Survival?
Review in Molecular neurobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Article
- Survival of compromised adult sensory neurons involves macrovesicular formation.Cell death discovery · 2022Article
- Sympathetic signaling facilitates progression of neuroendocrine prostate cancer.Cell death discovery · 2021Article
- Role of tumor suppressor molecules in genomic perturbations and damaged DNA repair involved in the pathogenesis of cancer and neurodegeneration (Review).Biomedical reports · 2020Review
- Neural invasion: a scenic trail for the nervous tumor and hidden therapeutic opportunity.American journal of cancer research · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The differential sensitivity of neurons to phosphatase and tensin homolog's (PTEN) lipid and protein phosphatase actions pose difficulties in defining the exact neuronal phenotype generated by targeting PTEN in neuronal injury. PTEN's biology beyond its phosphatase functions are also emerging. Considering spatial dynamics of PTEN a decisive factor for its mode of action we propose selective targeting of its cytoplasmic fraction a better therapeutic approach in neuronal injury.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.