ArticleImmunologic research2015
The epidemiological profile of ASIA syndrome after HPV vaccination: an evaluation based on the Vaccine Adverse Event Reporting Systems.
Article in Immunologic research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- SARS-CoV-2 vaccine-associated subacute thyroiditis: insights from a systematic review.Journal of endocrinological investigation · 2022Pooled it
- Severe manifestations of autoimmune syndrome induced by adjuvants (Shoenfeld's syndrome).Immunologic research · 2017Pooled it
- Vaccinations in paediatric rheumatology: an update on current developments.Current rheumatology reports · 2015Pooled it
- How to manage subacute thyroiditis.Drugs in context · 2026Review
- Insights into SARS-CoV-2-associated subacute thyroiditis: from infection to vaccine.Virology journal · 2023Review
- Graves' orbitopathy post-SARS-CoV-2 vaccines: report on six patients.Journal of endocrinological investigation · 2023Article
- Autoimmune and inflammatory thyroid diseases following vaccination with SARS-CoV-2 vaccines: from etiopathogenesis to clinical management.Endocrine · 2022Review
- Thyroid dysfunction following vaccination with COVID-19 vaccines: a basic review of the preliminary evidence.Journal of endocrinological investigation · 2022Review
- Cancer Immunotherapies: What the Perioperative Physician Needs to Know.Current oncology reports · 2022Review
- Graves' Disease after Administration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine in a Type 1 Diabetes Patient.Internal medicine (Tokyo, Japan) · 2022Article
- Thyroiditis following vaccination against COVID-19: Report of two cases and review of the literature.Metabolism open · 2021Article
- Reactive arthritis after COVID-19 vaccination.Human vaccines & immunotherapeutics · 2021Article
- Neuroimmunology: What Role for Autoimmunity, Neuroinflammation, and Small Fiber Neuropathy in Fibromyalgia, Chronic Fatigue Syndrome, and Adverse Events after Human Papillomavirus Vaccination?International journal of molecular sciences · 2019Review
- Addressing HPV vaccine myths: practical information for healthcare providers.Human vaccines & immunotherapeutics · 2019Review
- Autonomic dysfunction and HPV immunization: an overview.Immunologic research · 2018Review
- Safety of Human Papillomavirus Vaccines: An Updated Review.Drug safety · 2018Review
- Suspected Adverse Effects After Human Papillomavirus Vaccination: A Temporal Relationship Between Vaccine Administration and the Appearance of Symptoms in Japan.Drug safety · 2017Article
- Severe somatoform and dysautonomic syndromes after HPV vaccination: case series and review of literature.Immunologic research · 2017Review
- Involvement of chronic epipharyngitis in autoimmune (auto-inflammatory) syndrome induced by adjuvants (ASIA).Immunologic research · 2017Article
- Prof. Shoenfeld refers to Dr. Helen Petousis-Harris' attack on Dr. Manuel Martinez-Lavin's article. Clin Rheumatol 2016; 35: 833-834.Clinical rheumatology · 2016Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The term "ASIA-Autoimmune/inflammatory Syndrome Induced by Adjuvants" describes an umbrella of clinical conditions sharing similar signs or symptoms, including post-vaccination phenomena. No information is available on the epidemiology of the ASIA syndrome, especially following HPV vaccination. We carried out an analysis of the VAERS database to retrieve all cases of suspected ASIA syndrome according to the Shoenfeld and Agmon-Levin's guideline for the diagnosis. After causality assessment and case validation, 2,207 cases were considered probably or possibly related to vaccination. These represent the largest ASIA cohort ever reported and allowed us to estimate epidemiological and clinical characteristic of this syndrome. The commonest clinical manifestation observed were pyrexia (58%), myalgia (27%) and arthralgia or arthritis (19%), and the estimated reporting rate was of 3.6 cases per 100,000 doses of HPV vaccine distributed (95% CI 3.4-3.7). This study presents the first systematic estimation of ASIA incidence and expands the knowledge on this pathology. Further analyses are needed to identify genetic and non-genetic risk factors for ASIA syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.