Evidence map›Paper›PMID 25381124›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2015

Predictors of health-related quality of life perceived by end-stage renal disease patients under online hemodiafiltration.

Alexandra Moura, José Madureira, Pablo Alija, João Carlos Fernandes, José Gerardo Oliveira, Martin Lopez, Madalena Filgueiras, Leonilde Amado, Maria Sameiro-Faria, Vasco Miranda and 3 more

Abstract read
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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Effect of hemodiafiltration on measured physical activity: primary results of the HDFIT randomized controlled trial.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021
    Trial
  2. Trial
  3. Trial
  4. Trial
  5. Observational
  6. Developing, Analyzing, and Interpreting Outcome Assessments to Improve Endpoints in Infectious Diseases Clinical Research.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Impact of Hospitalization on the Quality of Life of Patients with Chronic Kidney Disease in Saudi Arabia.International journal of environmental research and public health · 2022
    Article
  11. CONVINCE in the context of existing evidence on haemodiafiltration.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2022
    Article
  12. Predictive model of variables associated with health-related quality of life in patients with advanced chronic kidney disease receiving hemodialysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alexandra MouraInstituto de Ciências da Saúde, Universidade Católica Portuguesa, Porto, Portugal.
José Madureira
Pablo Alija
João Carlos Fernandes
José Gerardo Oliveira
Martin Lopez
Madalena Filgueiras
Leonilde Amado
Maria Sameiro-Faria
Vasco Miranda
Edgar Mesquita
Alice Santos-Silva
Elísio Costa

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients' perception of health-related quality of life (HRQOL) is a consistent and powerful predictor of the outcome of end-stage renal disease (ESRD) patients under dialysis. This study aims to identify factors that could affect the HRQOL of ESRD patients under online hemodiafiltration (OL-HDF).

methodsWe evaluated 322 ESRD patients under OL-HDF (59.63% males; 64.9 ± 14.3 years old) from five dialysis units in the north of Portugal. Socio-demographic data, comorbidities, hematological data, iron status, dialysis adequacy, nutritional and inflammatory markers were collected from patients records. Patient's reported HRQOL score was assessed by using the Kidney Disease Quality of Life-Short Form (KDQOL-SF).

resultsESRD patients showed a mean (± SD) of 53.17% (± 15.31%) in SF-36 total score, 50.17% (± 9.51%) in the SF-36 mental component summary (MCS) and 49.75% (± 9.44%) in the SF-36 physical component summary (PCS). Red cell distribution width (RDW), feminine gender and diabetes were found as significant predictors of SF-36 total score of HRQOL, which accounts for 12% of the total explained variance. Patient satisfaction, RDW, body mass index and gender were identified as predictors for the PCS, which accounts for 22% of total explained variance. Furthermore, patient satisfaction and dry weight were found as predictors for MCS. These predictors accounted for 28% of the total explained variance.

conclusionsOur results showed that the coexistence of diabetes, gender and erythropoietic disturbances are predictors of HRQOL in patients under OL-HDF and suggest that more attention should be given to woman patients, to the improvement of anemia and to diabetic patients, who are more prone to perceive a worst HRQOL.

Indexed as

Health StatusHemodiafiltrationPatient SatisfactionAdultAgedBody Mass IndexComorbidityFemaleHumansKidney Failure, ChronicMaleMiddle AgedPerceptionPortugalQuality of Life

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.