ArticleArchives of virology1989
Interactions of Pseudorabies virus with swine alveolar macrophages I: virus replication.
Article in Archives of virology, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 41 citations in OpenAlex.
- Alveolar Macrophages in Viral Respiratory Infections: Sentinels and Saboteurs of Lung Defense.International journal of molecular sciences · 2025Review
- Macrophage Polarization in Virus-Host Interactions.Journal of clinical & cellular immunology · 2015Article
- Pathogenesis of natural and experimental Pseudorabies virus infections in dogs.Virology journal · 2015Article
- Targeting the porcine immune system--particulate vaccines in the 21st century.Developmental and comparative immunology · 2009Review
- Involvement of the matrix protein in attachment of porcine reproductive and respiratory syndrome virus to a heparinlike receptor on porcine alveolar macrophages.Journal of virology · 2002Article
- Study of immune function in inbred miniature pigs vaccinated and challenged with suid herpesvirus 1.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 1995Article
- Virus production and viral antigen expression in porcine blood monocytes inoculated with pseudorabies virus.Archives of virology · 1994Article
- Actinobacillus pleuropneumoniae culture supernatants interfere with killing of Pasteurella multocida by swine pulmonary alveolar macrophages.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 1993Article
- Effects of pseudorabies virus infection upon cytotoxicity and antiviral activities of porcine alveolar macrophages.Comparative immunology, microbiology and infectious diseases · 1992Article
- Rationale for using immunopotentiators in domestic food animals.Advances in veterinary science and comparative medicine · 1990Review
- Mutations in the Salmonella enterica serovar Choleraesuis cAMP-receptor protein gene lead to functional defects in the SPI-1 Type III secretion system.Veterinary researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The replication of Pseudorabies virus (PRV) in cultured swine alveolar macrophages (AM) was studied using 6 different virus strains. AM were highly permissive to PRV infection, with progeny virus titres of 10(7) TCID50/ml from some strains. Virus progeny titres were higher in cultures infected with the field strains S-62 and 4892 than in cultures infected with the strains Bartha or PRV-C. Virus replication, viral DNA synthesis and the concomitant cell damage were dependent upon virus input m.o.i.s. and virus strain. Furthermore, cells from 7 day old pigs yielded higher virus progeny titres than cells of 6 week old pigs. The results from this study provide support to the premise that PRV infection may predispose anials to respiratory disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.