Evidence map›Paper›PMID 25380678›Full record

ArticleDysphagia2015

Safety and Efficacy of Oral Feeding in Infants with BPD on Nasal CPAP.

Melissa Hanin, Sushma Nuthakki, Manish B Malkar, Sudarshan R Jadcherla

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Dysphagia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05446389 (The Use of the Pacifier Activated Lullaby to Improve the Transition to Oral Feeding for Premature Infants With Chronic Lung Disease or Respiratory Distress Syndrome), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05446389 naterminatednot on this mapstarted 2022, after this paper: background citation

The Use of the Pacifier Activated Lullaby to Improve the Transition to Oral Feeding for Premature Infants With Chronic Lung Disease or Respiratory Distress Syndrome

TypeinterventionalSponsorUniversity of Missouri-ColumbiaRan2022 to 2025Enrolled33ConditionsChronic Lung Disease of Prematurity, Respiratory Distress Syndrome in Premature Infant, Bronchopulmonary Dysplasia, Preterm BirthArmsPacifier Activated Lullaby ®
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Review
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  9. Review
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  11. Article
  12. Oral-feeding guidelines for preterm neonates in the NICU: a scoping review.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Article
  13. The effects of oral feeding while on nasal continuous positive airway pressure (NCPAP) in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Article
  14. Article
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  19. Effect of nasal continuous positive airway pressure on the pharyngeal swallow in neonates.Journal of perinatology : official journal of the California Perinatal Association · 2017
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Melissa HaninDepartment of Neonatal Occupational Therapy, Nationwide Children's Hospital, Columbus, OH, 43205, USA.
Sushma Nuthakki
Manish B Malkar
Sudarshan R Jadcherla
The Ohio State University · USBaylor College of Medicine · USNationwide Children's Hospital · US

Funding

The Physiology of the Pharyngo-Esophageal JunctionP01DK068051 · NIDDK · MEDICAL COLLEGE OF WISCONSIN · PI SHAKER, REZA NONE · 2007 to 2018
$11.6M
Pathophysiology of Aerodigestive Reflexes in InfantsR01DK068158 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI JADCHERLA, SUDARSHAN R · 2006 to 2016
$3.7M
NIDDK NIH HHS P01 DK068051NIDDK NIH HHS R01 DK068158
6 · The paper itself

Abstract

Safety and efficacy of oral feeding was examined in infants with bronchopulmonary dysplasia (BPD) on nasal continuous positive airway pressure (NCPAP). We hypothesized that repetitive oral feeding enhances aero-digestive outcomes and reduces resource utilization. Data from infants with BPD (37-42 weeks post menstrual age) that were orally fed while on NCPAP (n = 26) were compared with those that were exclusively gavage fed on NCPAP (n = 27). Subject assignment was random and physician practice based. Specifically, we compared the differences in aero-digestive milestones, resource utilization, and safety metrics. Demographic characteristics such as gender distribution, gestational age, and birth weight, clinical characteristics such as frequency of intraventricular hemorrhage and patent ductus arteriosus needing surgical ligation were similar in both groups (p > 0.05). Characteristics of respiratory support and airway milestones were similar in both groups (p > 0.05). However, infants in NCPAP-oral fed group had earlier acquisition of full oral feeding milestone by 17 days (median) versus infants who were not orally fed during NCPAP (p < 0.05). Discharge weights and the frequency of gastrostomy tube placement were also similar in both groups (p > 0.05). There were no tracheostomies in either group. There was no incidence of clinically significant aspiration pneumonia in infants during the period of the oral feeding while on NCPAP. Controlled introduction of oral feedings in infants with BPD during NCPAP is safe and may accelerate the acquisition of oral feeding milestones.

Indexed as

Bottle FeedingContinuous Positive Airway PressureEnteral NutritionBronchopulmonary DysplasiaDuctus Arteriosus, PatentFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesTime Factors

Identifiers

PMID25380678
PMCPMC4800480
OpenAlexW2010198430

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.