ArticleACS nano2014
Fixed-gap tunnel junction for reading DNA nucleotides.
Article in ACS nano, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Fingerprint Recognition Based on Molecular-Scale Conductance Response via Electrochemically Gated Quantum Tunnelling.Sensors (Basel, Switzerland) · 2026Article
- Decoding information stored in DNAs through single-molecule electrical detection platforms.Innovation (Cambridge (Mass.)) · 2025Review
- Conducting Atomic Force Microscopy of Protein Wires.Small (Weinheim an der Bergstrasse, Germany) · 2025Article
- Electromigrated Gold Nanogap Tunnel Junction Arrays: Fabrication and Electrical Behavior in Liquid and Gaseous Media.ACS applied materials & interfaces · 2024Article
- Functionalized electrodes embedded in nanopores: read-out enhancement?Chemistry, an Asian journal · 2023Review
- Combined quantum tunnelling and dielectrophoretic trapping for molecular analysis at ultra-low analyte concentrations.Nature communications · 2021Article
- Article
- Detecting Single-Nucleotides by Tunneling Current Measurements at Sub-MHz Temporal Resolution.Sensors (Basel, Switzerland) · 2017Article
- Solid-state nanopore localization by controlled breakdown of selectively thinned membranes.Nanotechnology · 2017Article
- Wafer-scale integration of sacrificial nanofluidic chips for detecting and manipulating single DNA molecules.Nature communications · 2017Article
- Classification of DNA nucleotides with transverse tunneling currents.Nanotechnology · 2017Article
- Observation of Giant Conductance Fluctuations in a Protein.Nano futures · 2017Article
- Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling.Nature communications · 2016Article
- Tailoring particle translocation via dielectrophoresis in pore channels.Scientific reports · 2016Article
- The promises and challenges of solid-state sequencing.Nature nanotechnology · 2016Article
- Article
- Click Addition of a DNA Thread to the N-Termini of Peptides for Their Translocation through Solid-State Nanopores.ACS nano · 2015Article
- Physical model for recognition tunneling.Nanotechnology · 2015Article
- Nanopore-based fourth-generation DNA sequencing technology.Genomics, proteomics & bioinformatics · 2015Review
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
Previous measurements of the electronic conductance of DNA nucleotides or amino acids have used tunnel junctions in which the gap is mechanically adjusted, such as scanning tunneling microscopes or mechanically controllable break junctions. Fixed-junction devices have, at best, detected the passage of whole DNA molecules without yielding chemical information. Here, we report on a layered tunnel junction in which the tunnel gap is defined by a dielectric layer, deposited by atomic layer deposition. Reactive ion etching is used to drill a hole through the layers so that the tunnel junction can be exposed to molecules in solution. When the metal electrodes are functionalized with recognition molecules that capture DNA nucleotides via hydrogen bonds, the identities of the individual nucleotides are revealed by characteristic features of the fluctuating tunnel current associated with single-molecule binding events.
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Registered trials
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