Evidence map›Paper›PMID 25380248›Full record

ArticlePloS one2014

A longitudinal assessment of sleep timing, circadian phase, and phase angle of entrainment across human adolescence.

Stephanie J Crowley, Eliza Van Reen, Monique K LeBourgeois, Christine Acebo, Leila Tarokh, Ronald Seifer, David H Barker, Mary A Carskadon

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 3 pooled it
14.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 3 syntheses or guidelines pooled it, 260 citations in OpenAlex.

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73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Stephanie J CrowleyBiological Rhythms Research Laboratory, Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, United States of America.
Eliza Van ReenE.P. Bradley Hospital Sleep Research Laboratory, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, United States of America.
Monique K LeBourgeoisSleep and Development Laboratory, Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, United States of America.
Christine AceboE.P. Bradley Hospital Sleep Research Laboratory, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, United States of America.
Leila TarokhE.P. Bradley Hospital Sleep Research Laboratory, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, United States of America; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland; University Hospital of Child and Adolescent Psychiatry, University of Bern, Bern, Switzerland.
Ronald SeiferE.P. Bradley Hospital Sleep Research Laboratory, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, United States of America; The Bradley Hasbro Children's Research Center, Providence, RI, United States of America.
David H BarkerE.P. Bradley Hospital Sleep Research Laboratory, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, United States of America; The Bradley Hasbro Children's Research Center, Providence, RI, United States of America.
Mary A CarskadonE.P. Bradley Hospital Sleep Research Laboratory, Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, United States of America; Centre for Sleep Research, University of South Australia, Adelaide, Australia.
Bradley Hospital · USBrown University · USProvidence College · USRush University Medical Center · USUniversity of Colorado Boulder · USUniversity of Zurich · CH

Funding

Alcohol, Sleep and Circadian Rhythms in Young HumansR01AA013252 · NIAAA · EMMA PENDLETON BRADLEY HOSPITAL · PI CARSKADON, MARY A · 2001 to 2005
$3.6M
NIAAA NIH HHS AA 13252NIAAA NIH HHS R01 AA013252
6 · The paper itself

Abstract

The aim of this descriptive analysis was to examine sleep timing, circadian phase, and phase angle of entrainment across adolescence in a longitudinal study design. Ninety-four adolescents participated; 38 (21 boys) were 9-10 years ("younger cohort") and 56 (30 boys) were 15-16 years ("older cohort") at the baseline assessment. Participants completed a baseline and then follow-up assessments approximately every six months for 2.5 years. At each assessment, participants wore a wrist actigraph for at least one week at home to measure self-selected sleep timing before salivary dim light melatonin onset (DLMO) phase - a marker of the circadian timing system - was measured in the laboratory. Weekday and weekend sleep onset and offset and weekend-weekday differences were derived from actigraphy. Phase angles were the time durations from DLMO to weekday sleep onset and offset times. Each cohort showed later sleep onset (weekend and weekday), later weekend sleep offset, and later DLMO with age. Weekday sleep offset shifted earlier with age in the younger cohort and later in the older cohort after age 17. Weekend-weekday sleep offset differences increased with age in the younger cohort and decreased in the older cohort after age 17. DLMO to sleep offset phase angle narrowed with age in the younger cohort and became broader in the older cohort. The older cohort had a wider sleep onset phase angle compared to the younger cohort; however, an age-related phase angle increase was seen in the younger cohort only. Individual differences were seen in these developmental trajectories. This descriptive study indicated that circadian phase and self-selected sleep delayed across adolescence, though school-day sleep offset advanced until no longer in high school, whereupon offset was later. Phase angle changes are described as an interaction of developmental changes in sleep regulation interacting with psychosocial factors (e.g., bedtime autonomy).

Indexed as

Circadian RhythmActigraphyAdolescentAgingChildFemaleHumansLongitudinal StudiesMaleMelatoninSalivaSex CharacteristicsSleepTime FactorsMelatonin

Identifiers

PMID25380248
PMCPMC4224451
OpenAlexW2090080078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.