Evidence map›Paper›PMID 25379987›Full record

ArticleBioEssays : news and reviews in molecular, cellular and developmental biology2015

On a matter of seminal importance.

Lisa A McGraw, Susan S Suarez, Mariana F Wolfner

Abstract read
In one paragraph

Article in BioEssays : news and reviews in molecular, cellular and developmental biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
68.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
  2. Review
  3. Role of Seminal Exosomes in Reproduction.Journal of cellular physiology · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. CRISPR/Cas9-mediatedFrontiers in physiology · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Seminal Plasma: Relevant for Fertility?International journal of molecular sciences · 2021
    Review
  16. Review
  17. Article
  18. ThePhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  19. Article
  20. Male reproductive aging arises via multifaceted mating-dependent sperm and seminal proteome declines, but is postponable inProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lisa A McGrawDepartment of Biological Sciences, NC State University, Raleigh, NC, USA.
Susan S Suarez
Mariana F Wolfner
Cornell University · USNorth Central State College · US

Funding

ACTIONS OF SEMINAL PROTEINS IN MATED DROSOPHILA FEMALESR01HD038921 · NICHD · CORNELL UNIVERSITY ITHACA · PI WOLFNER, MARIANA FEDERICA · 2000 to 2019
$5.6M
"Physical and Chemical Cues that Guide Sperm Migration"R01HD070038 · NICHD · CORNELL UNIVERSITY · PI SUAREZ, SUSAN STEVENS, WU, MINGMING · 2012 to 2014
$880k
NICHD NIH HHS R01 HD038921NICHD NIH HHS R01-HD038921NICHD NIH HHS R01 HD070038NICHD NIH HHS R01-HD070038
6 · The paper itself

Abstract

Egg and sperm have, understandably, been the "stars" of mammalian fertilization biology, particularly because artificial reproductive technologies allow for fertilization to occur outside of the female reproductive tract without other apparent contributions from either sex. Yet, recent research, including an exciting new paper, reveals unexpected and important contributions of seminal plasma to fertility. For example, seminal plasma proteins play critical roles in modulating female reproductive physiology, and a new study in mice demonstrates that effects of some of these proteins on the female can even affect the health of her progeny. Furthermore, although several actions of seminal plasma have been conserved across taxa, male accessory glands and their products are diverse - even among mammals. Taken together, these studies suggest that the actions of seminal plasma components are important to understand, and also to consider in future development of assisted reproductive technologies (ART) for humans, farm species and endangered species of mammals.

Indexed as

AnimalsFemaleHumansMaleMiceReproductionSemenSeminal Plasma ProteinsSeminal Plasma Proteinsaccessory sex glandsinsect fertilitymammalian fertilityoffspring healthreproductionreproductive tract physiologyseminal proteins

Identifiers

PMID25379987
PMCPMC4502980
OpenAlexW1622646651

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.