Evidence map›Paper›PMID 25379673›Full record

ArticlePloS one2014

A comparison between the EQ-5D and the SF-6D in patients with chronic obstructive pulmonary disease (COPD).

Jing Chen, Carlos K H Wong, Sarah M McGhee, Polly K P Pang, Wai-Cho Yu

Registry-linked trialOpen access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04377464 (COVID-19 - Quality of Life After Infection), which is not on this map. Cited by 25 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 5 pooled it
14.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04377464 unknown statusnot on this mapstarted 2020, after this paper: background citation

COVID-19 - Quality of Life After Infection

TypeobservationalSponsorChinese University of Hong KongRan2020 to 2022Enrolled200ConditionsCOVID-19, Quality of LifeArmsSF12, EQ-5D-5L and work status standardized quantitative assessments
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 51 citations in OpenAlex.

  1. Measurement properties of preference-based measures for economic evaluation in COPD: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Pooled it
  2. Pooled it
  3. The quality of life in Chinese population with chronic non-communicable diseases according to EQ-5D-3L: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Pooled it
  4. Utility scores for different health states related to depression: individual participant data analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017
    Pooled it
  5. A Systematic Literature Review of the Humanistic Burden of COPD.International journal of chronic obstructive pulmonary disease
    Pooled it
  6. Trial
  7. Article
  8. The Humanistic and Economic Burden of COPD Patients in Urban China: A Propensity Score Matching Study.International journal of chronic obstructive pulmonary disease · 2025
    Article
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  15. Evaluating a falls prevention intervention in older home care recipients: a comparison of SF-6D and EQ-5D.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
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  20. Changes in biopsychosocial outcomes for a mixed cohort of ICU survivors.The South African journal of physiotherapy · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jing ChenSchool of Public Health, The University of Hong Kong, Hong Kong, China.
Carlos K H WongDepartment of Family Medicine and Primary Care, The University of Hong Kong, Hong Kong, China.
Sarah M McGheeSchool of Public Health, The University of Hong Kong, Hong Kong, China.
Polly K P PangDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China.
Wai-Cho YuDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China.
University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe appropriate use of generic preference-based measures determines the accuracy of disease assessment and further decision on healthcare policy using quality adjusted life years. The discriminative capacity of different instruments would differ across disease groups. Our study was to examine the difference in utility scores for COPD patients measured by EQ-5D and SF-6D and to assist the choice of a proper instrument in this disease group.

methodsDifferences of mean utility scores of EQ-5D and SF-6D in groups defined by socio-demographic characteristics, comorbidities, health service utilisation and severity of illness were tested using Mann-Whitney test, t-test, Kruskal-Wallis test, Pearson's correlation coefficient and ANOVA, as appropriate. The discriminative properties of the two instruments were compared against indicators of quality of life using receiver operating characteristic curves. The statistical significance of the area under the curves (AUC) was tested by ANOVA and F-statistics used to compare the efficiency with which each instrument discriminated between disease severity groups.

resultsMean utility scores of EQ-5D and SF-6D were 0.644 and 0.629 respectively in the 154 subjects included in the analysis. EQ-5D scores were significantly higher than SF-6D in groups less severe and these differences corresponded to a minimally important difference of greater than 0.03 (p<0.001). EQ-5D and SF-6D scores were strongly correlated across the whole sample (r = 0.677, p<0.001) and in pre-defined groups (r>0.5 and p<0.05 for all correlation coefficients). AUCs were above 0.5 against the indicators of health-related quality of life for both instruments. F-ratios suggested SF-6D was more efficient in discriminating cases of different disease severity than EQ-5D.

conclusionsBoth EQ-5D and SF-6D appeared to be valid preference-based measures in Chinese COPD patients. SF-6D was more efficient in detecting differences among subgroups with differing health status. EQ-5D and SF-6D measured different things and might not be used interchangeably in COPD patients.

Indexed as

Health Status IndicatorsQuality-Adjusted Life YearsActivities of Daily LivingAgedAged, 80 and overAnalysis of VarianceFemaleHumansMaleMiddle AgedPulmonary Disease, Chronic ObstructiveReproducibility of ResultsSeverity of Illness IndexSurveys and Questionnaires

Identifiers

PMID25379673
PMCPMC4224433
OpenAlexW2060969535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.