Evidence map›Paper›PMID 25379545›Full record

SynthesisTheScientificWorldJournal2014

Antimicrobial photodynamic therapy and dental plaque: a systematic review of the literature.

G C Santin, D S B Oliveira, R Galo, M C Borsatto, S A M Corona

Abstract readSystematic Review
In one paragraph

Synthesis in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Nanotechnology for Dentistry: Prospects and Applications.Nanomaterials (Basel, Switzerland) · 2023
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Photodynamic Inactivation ofInternational journal of molecular sciences · 2021
    Article
  17. Review
  18. Effect of a Combination of Photodynamic Therapy and Chitosan onJournal of lasers in medical sciences · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

G C SantinDepartment of Pediatric Clinics, Preventive and Community Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
D S B OliveiraDepartment of Pediatric Clinics, Preventive and Community Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
R GaloDepartment of Prosthesis and Dental Materials, Dental School of Araraquara, São Paulo State University, Araraquara, SP, Brazil.
M C BorsattoDepartment of Pediatric Clinics, Preventive and Community Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil.
S A M CoronaDepartment of Restorative Dentistry, Dental School of Ribeirão Preto, University of São Paulo, Avenida do Café, s/n, Monte Alegre, 14040-904 Ribeirão Preto, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to perform a systematic review of the literature on the efficacy of antimicrobial photodynamic therapy (PDTa) on cariogenic dental biofilm. TYPES OF STUDIES REVIEWED: Studies in vivo, in vitro, and in situ were included. Articles that did not address PDTa, those that did not involve cariogenic biofilm, those that used microorganisms in the plankton phase, and reviews were excluded. Data extraction and quality assessments were performed independently by two raters using a scale.

resultsTwo hundred forty articles were retrieved; only seventeen of them met the eligibility criteria and were analyzed in the present review. Considerable variability was found regarding the methodologies and application protocols for antimicrobial PDTa. Two articles reported unfavorable results. PRACTICAL IMPLICATIONS: The present systematic review does not allow drawing any concrete conclusions regarding the efficacy of antimicrobial PDTa, although this method seems to be a promising option.

Indexed as

PhotochemotherapyBiofilmsDental CariesDental PlaqueHumansLightMethylene BluePhotosensitizing AgentsStreptococcusTolonium ChlorideMethylene BluePhotosensitizing AgentsTolonium Chloride

Identifiers

PMID25379545
PMCPMC4212597

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.