Evidence map›Paper›PMID 25379541›Full record

Trial reportTheScientificWorldJournal2014

Spinal anaesthesia with hyperbaric prilocaine in day-case perianal surgery: randomised controlled trial.

Ozden Gorgoz Kaban, Dilek Yazicioglu, Taylan Akkaya, M Murat Sayin, Duray Seker, Haluk Gumus

Erratum issued Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04367818 (Could Peri-anal Block be Effective as Caudal Block in Trans-anal Pull-through Surgery for Children With Hirschsprung Disease??. A Randomized Controlled Trial.), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04367818 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Could Peri-anal Block be Effective as Caudal Block in Trans-anal Pull-through Surgery for Children With Hirschsprung Disease??. A Randomized Controlled Trial.

TypeinterventionalSponsorAssiut UniversityRan2021 to 2022Enrolled60ConditionsAnalgesiaArmsPeri-anal local anaesthetic infiltration, Caudal anaesthesia
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ozden Gorgoz KabanMinistry of Health, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Caddesi 112 Altındağ, Akasya Sokak 9/10 Koru Mah. Cayyolu, 06810 Ankara, Turkey.
Dilek YaziciogluMinistry of Health, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Caddesi 112 Altındağ, Akasya Sokak 9/10 Koru Mah. Cayyolu, 06810 Ankara, Turkey.
Taylan AkkayaMinistry of Health, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Caddesi 112 Altındağ, Akasya Sokak 9/10 Koru Mah. Cayyolu, 06810 Ankara, Turkey.
M Murat SayinMinistry of Health, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Caddesi 112 Altındağ, Akasya Sokak 9/10 Koru Mah. Cayyolu, 06810 Ankara, Turkey.
Duray SekerMinistry of Health, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Caddesi 112 Altındağ, Akasya Sokak 9/10 Koru Mah. Cayyolu, 06810 Ankara, Turkey.
Haluk GumusMinistry of Health, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Caddesi 112 Altındağ, Akasya Sokak 9/10 Koru Mah. Cayyolu, 06810 Ankara, Turkey.
Ministry of Health · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe local anaesthetics used in day-case spinal anaesthesia should provide short recovery times. We aimed to compare hyperbaric prilocaine and bupivacaine in terms of sensory block resolution and time to home readiness in day-case spinal anaesthesia. MeTHODS: Fifty patients undergoing perianal surgery were randomized into two groups. The bupivacaine-fentanyl group (Group B) received 7.5 mg, 0.5% hyperbaric bupivacaine + 20 μg fentanyl in total 1.9 mL. The prilocaine-fentanyl group (Group P) received 30 mg, 0.5% hyperbaric prilocaine + 20 μg fentanyl in the same volume.

resultsTime to L1 block and maximum block was shorter in Group P than in Group B (Group P 4.6 ± 1.3 min versus Group B 5.9 ± 01.9 min, P = 0.017, and Group P 13.2 ± 7.5 min versus Group B 15.3 ± 6.6 min, P = 0.04). The time to L1 regression and S3 regression of the sensorial block was significantly shorter in Group P than in Group B (45.7 ± 21.9 min versus 59.7 ± 20.9 min, P = 0.024, and 133.8 ± 41.4 min versus 200.4 ± 64.8 min, P < 0.001). The mean time to home readiness was shorter for Group P than for Group B (155 ± 100.2 min versus 207.2 ± 62.7 min (P < 0.001)).

conclusionDay-case spinal anaesthesia with hyperbaric prilocaine + fentanyl is superior to hyperbaric bupivacaine in terms of earlier sensory block resolution and home readiness and the surgical conditions are comparable for perianal surgery.

Indexed as

Anesthetics, LocalBupivacaineFentanylPrilocaineAdultAmbulatory Surgical ProceduresAnal CanalAnesthesia, SpinalDrug CombinationsFemaleHumansMaleMiddle AgedNerve BlockAnesthetics, LocalBupivacaineDrug CombinationsFentanylPrilocaine

Identifiers

PMID25379541
PMCPMC4214037
OpenAlexW2158933355

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.