Evidence map›Paper›PMID 25379519›Full record

ArticleTheScientificWorldJournal2014

Bone mineral density at diagnosis of celiac disease and after 1 year of gluten-free diet.

Stefano Pantaleoni, Massimo Luchino, Alessandro Adriani, Rinaldo Pellicano, Davide Stradella, Davide Giuseppe Ribaldone, Nicoletta Sapone, Gian Carlo Isaia, Marco Di Stefano, Marco Astegiano

Open access · goldAbstract read
In one paragraph

Article in TheScientificWorldJournal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Editorial: Celiac disease in children.Frontiers in pediatrics · 2025
    Article
  5. Review
  6. Observational
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Celiac disease in children: A review of the literature.World journal of clinical pediatrics · 2021
    Review
  13. Bone Mineral Density Screening and the Frequency of Osteopenia/Osteoporosis in Turkish Adult Patients With Celiac Disease.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2021
    Article
  14. Bone health: an important consideration in coeliac disease.Gastroenterology and hepatology from bed to bench · 2020
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Stefano PantaleoniDepartment of Gastroenterology, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Massimo LuchinoDepartment of Gastroenterology, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Alessandro AdrianiDepartment of Gastroenterology, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Rinaldo PellicanoDepartment of Gastroenterology, Molinette Hospital, University of Turin, 10126 Turin, Italy ; Clinic of Gastroenterology and Hepatology, Via Cavour 31, 10123 Turin, Italy.
Davide StradellaDepartment of Gastroenterology, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Davide Giuseppe RibaldoneDepartment of Gastroenterology, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Nicoletta SaponeDepartment of Gastroenterology, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Gian Carlo IsaiaGerontology and Bone Metabolic Disease Section, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Marco Di StefanoGerontology and Bone Metabolic Disease Section, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Marco AstegianoDepartment of Gastroenterology, Molinette Hospital, University of Turin, 10126 Turin, Italy.
Fondazione Ricerca Molinette · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atypical or silent celiac disease may go undiagnosed for many years and can frequently lead to loss of bone mineral density, with evolution to osteopenia or osteoporosis. The prevalence of the latter conditions, in case of new diagnosis of celiac disease, has been evaluated in many studies but, due to the variability of epidemiologic data and patient features, the results are contradictory. The aim of this study was to evaluate bone mineral density by dual-energy X-ray absorptiometry in 175 consecutive celiac patients at time of diagnosis (169 per-protocol, 23 males, 146 females; average age 38.9 years). Dual-energy X-ray absorptiometry was repeated after 1 year of gluten-free diet in those with T-score value <-1 at diagnosis. Stratification of patients according to sex and age showed a higher prevalence of low bone mineral density in men older than 30 years and in women of all ages. A 1-year gluten-free diet led to a significant improvement in lumbar spine and femoral neck mean T-score value. We propose that dual-energy X-ray absorptiometry should be performed at diagnosis of celiac disease in all women and in male aged >30 years, taking into account each risk factor in single patients.

Indexed as

Bone DensityDiet, Gluten-FreeAbsorptiometry, PhotonAdultBone Diseases, MetabolicCeliac DiseaseFemaleFemur NeckHumansLumbar VertebraeMaleMiddle AgedOsteoporosisRisk Factors

Identifiers

PMID25379519
PMCPMC4213989
OpenAlexW2042475450

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.