ArticleNeuroImage. Clinical2014
Cerebellar language mapping and cerebral language dominance in pediatric epilepsy surgery patients.
Article in NeuroImage. Clinical, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Systematic Review and Meta-analysis of Language Symptoms due to Cerebellar Injury.Cerebellum (London, England) · 2023Pooled it
- Association between perioperative factors and the occurrence of postoperative cerebellar mutism syndrome in children.Frontiers in neurology · 2026Article
- FMRI activation during paragraph reading in pediatric epilepsy.Epilepsy & behavior : E&B · 2025Article
- Neural adaptations in short-term learning of sign language revealed by fMRI and DTI.Scientific reports · 2025Article
- Long-term neuroplasticity in language networks after anterior temporal lobe resection.Epilepsia · 2025Article
- MRI radiomics combined with machine learning for diagnosing mild cognitive impairment: a focus on the cerebellar gray and white matter.Frontiers in aging neuroscience · 2024Article
- Cerebellar white and gray matter abnormalities in temporal lobe epilepsy: a voxel-based morphometry study.Frontiers in neuroscience · 2024Article
- Resting-state functional alterations in patients with brain arteriovenous malformations involving language areas.Human brain mapping · 2023Article
- Language lateralization mapping (reversibly) masked by non-dominant focal epilepsy: a case report.Frontiers in human neuroscience · 2023Article
- Cerebellar volumes and language functions in school-aged children born very preterm.Pediatric research · 2021Article
- Utility of MRI, PET, and ictal SPECT in presurgical evaluation of non-lesional pediatric epilepsy.Seizure · 2020Review
- Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence.Cerebellum (London, England) · 2020Article
- Language Cerebro-cerebellar Reorganization in Children After Surgery of Right Cerebellar Astrocytoma: a fMRI Study.Cerebellum (London, England) · 2019Article
- An adaptive semantic matching paradigm for reliable and valid language mapping in individuals with aphasia.Human brain mapping · 2018Article
- Paradoxical Activation in the Cerebellum During Language fMRI in Patients with Brain Tumors: Possible Explanations Based on Neurovascular Uncoupling and Functional Reorganization.Cerebellum (London, England) · 2018Article
- Cerebellar Asymmetry and Cortical Connectivity in Monozygotic Twins with Discordant Handedness.Cerebellum (London, England) · 2018Article
- Language lateralization during the Chinese semantic task relates to the contralateral cerebra-cerebellar interactions at rest.Scientific reports · 2017Article
- How Auditory Experience Differentially Influences the Function of Left and Right Superior Temporal Cortices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Pediatric brain MRI, Part 2: Advanced techniques.Pediatric radiology · 2017Review
- Diffusion Tensor Tractography of the Cerebellar Peduncles in Prematurely Born 7-Year-Old Children.Cerebellum (London, England) · 2017Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveChildren with epilepsy often have reorganization of language networks and abnormal brain anatomy, making determination of language lateralization difficult. We characterized the proportion and distribution of language task activation in the cerebellum to determine the relationship to cerebral language lateralization.
methodsForty-six pediatric epilepsy surgery candidates (aged 7-19 years) completed an fMRI auditory semantic decision language task. Distribution of activated voxels and language laterality indices were computed using: (a) Broca's and Wernicke's areas and their right cerebral homologues; and (b) left and right cerebellar hemispheres. Language task activation was anatomically localized in the cerebellum.
resultsLateralized language task activation in either cerebral hemisphere was highly correlated with lateralized language task activation in the contralateral cerebellar hemisphere (Broca vs. cerebellar: ρ = -0.54, p < 0.01). Cerebellar language activation was located within Crus I/II, areas previously implicated in non-motor functional networks.
conclusionsCerebellar language activation occurs in homologous regions of Crus I/II contralateral to cerebral language activation in patients with both right and left cerebral language dominance. Cerebellar language laterality could contribute to comprehensive pre-operative evaluation of language lateralization in pediatric epilepsy surgery patients. Our data suggest that patients with atypical cerebellar language activation are at risk for having atypical cerebral language organization.
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