Evidence map›Paper›PMID 25379397›Full record

ArticleMedical mycology case reports2014

Pneumocystis jirovecii pneumonia following everolimus treatment of metastatic breast cancer.

Kelvin Teck-Hong Kuik, Jason Trubiano, Leon J Worth, Nur-Shirin Harun, Daniel Steinfort, Douglas Johnson

Open access · goldAbstract read
In one paragraph

Article in Medical mycology case reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kelvin Teck-Hong KuikDepartment of General Medicine, Peter MacCallum Cancer Centre, East Melbourne, Australia.
Jason TrubianoDepartment of Infectious Diseases, Peter MacCallum Cancer Centre, East Melbourne, Australia.
Leon J WorthDepartment of Infectious Diseases, Peter MacCallum Cancer Centre, East Melbourne, Australia ; Department of Medicine, University of Melbourne, Parkville, Australia.
Nur-Shirin HarunDepartment of General Medicine, Peter MacCallum Cancer Centre, East Melbourne, Australia.
Daniel SteinfortDepartment of General Medicine, Peter MacCallum Cancer Centre, East Melbourne, Australia.
Douglas JohnsonDepartment of General Medicine, Peter MacCallum Cancer Centre, East Melbourne, Australia.
Peter MacCallum Cancer Centre · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Everolimus is an inhibitor of mammalian target of rapamycin with anti-tumour activity. While everolimus is known to cause drug-induced pneumonitis, it is rarely associated with Pneumocystis jirovecii pneumonia (PJP). We report a patient on everolimus therapy for metastatic breast cancer that developed PJP. Diagnosis was based on clinical features and a quantitative polymerase chain reaction for P. jirovecii DNA. Clinicians should consider PJP as a potential cause of pulmonary infiltrates in patients treated with everolimus.

Indexed as

CancerEverolimusPJPPneumocystisPneumonitis

Identifiers

PMID25379397
PMCPMC4216328
OpenAlexW2087855411

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.