Evidence map›Paper›PMID 25379338›Full record

ArticleMycology2014

An assessment of natural product discovery from marine (

David P Overy, Paul Bayman, Russell G Kerr, Gerald F Bills

Abstract read
In one paragraph

Article in Mycology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Two New SexualJournal of fungi (Basel, Switzerland) · 2021
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. The Neglected Marine Fungi,Marine drugs · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

David P OveryDepartment of Chemistry, University of Prince Edward Island , 550 University Ave., Charlottetown , Prince Edward Island , Canada C1A 4P3 ; Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island , 550 University Ave., Charlottetown , Prince Edward Island , Canada C1A 4P3 ; Nautilus Biosciences Canada, Duffy Research Center, University of Prince Edward Island , 550 University Ave., Charlottetown , Prince Edward Island , Canada C1A 4P3.
Paul BaymanDepartment of Biology, University of Puerto Rico-Río Piedras , P. O. Box 23360, San Juan 00931 , Puerto Rico.
Russell G KerrDepartment of Chemistry, University of Prince Edward Island , 550 University Ave., Charlottetown , Prince Edward Island , Canada C1A 4P3 ; Department of Biomedical Sciences, Atlantic Veterinary College, University of Prince Edward Island , 550 University Ave., Charlottetown , Prince Edward Island , Canada C1A 4P3 ; Nautilus Biosciences Canada, Duffy Research Center, University of Prince Edward Island , 550 University Ave., Charlottetown , Prince Edward Island , Canada C1A 4P3.
Gerald F BillsTexas Therapeutics Institute, The Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center , 1881 East Rd., Houston , TX 77054 , USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural products community has been investigating secondary metabolites from marine fungi for several decades, but when one attempts to search for validated reports of new natural products from marine fungi, one encounters a literature saturated with reports from 'marine-derived' fungi. Of the 1000+ metabolites that have been characterized to date, only approximately 80 of these have been isolated from species from exclusively marine lineages. These metabolites are summarized here along with the lifestyle and habitats of their producing organisms. Furthermore, we address some of the reasons for the apparent disconnect between the stated objectives of discovering new chemistry from marine organisms and the apparent neglect of the truly exceptional obligate marine fungi. We also offer suggestions on how to reinvigorate enthusiasm for marine natural products discovery from fungi from exclusive marine lineages and highlight the need for critically assessing the role of apparently terrestrial fungi in the marine environment.

Indexed as

marine biodiversitymarine mycologyosmotolerancesecondary metabolites

Identifiers

PMID25379338
PMCPMC4205923

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.