Evidence map›Paper›PMID 25379166›Full record

ArticleChemical science2014

Late-stage [

Allen F Brooks, Joseph J Topczewski, Naoko Ichiishi, Melanie S Sanford, Peter J H Scott

Abstract read
In one paragraph

Article in Chemical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed.

  1. Article
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  3. Deoxyfluorination of Hydroxy-Substituted Boronates.ACS organic & inorganic Au · 2026
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  4. Trifluoromethylation of alkyl electrophiles withScience (New York, N.Y.) · 2025
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  7. From Inhibitors to PET: SAR-Based Development of [Journal of medicinal chemistry · 2025
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  8. Review
  9. Simple and Efficient Synthesis ofPharmaceuticals (Basel, Switzerland) · 2024
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  10. C-H Labeling with [ACS central science · 2024
    Review
  11. Automation of Copper-MediatedMolecules (Basel, Switzerland) · 2024
    Article
  12. Manufacturing 6-[Organic letters · 2024
    Article
  13. Photoredox Nucleophilic (Radio)fluorination of Alkoxyamines.Journal of the American Chemical Society · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Automated sulfur-[Reaction chemistry & engineering · 2023
    Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Allen F BrooksDepartment of Radiology, The University of Michigan Medical School Ann Arbor MI, USA.
Joseph J TopczewskiDepartment of Chemistry, The University of Michigan, Ann Arbor MI, USA.
Naoko IchiishiDepartment of Chemistry, The University of Michigan, Ann Arbor MI, USA.
Melanie S SanfordDepartment of Chemistry, The University of Michigan, Ann Arbor MI, USA.
Peter J H ScottDepartment of Radiology, The University of Michigan Medical School Ann Arbor MI, USA ; The Interdepartmental Program in Medicinal Chemistry The University of Michigan, Ann Arbor MI, USA.

Funding

C-H Bond Functionalization in Organic SynthesisR01GM073836 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANFORD, MELANIE S. · 2005 to 2019
$4.0M
Training Future Imaging Scientists for BiomedicineT32EB005172 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FOWLKES, JEFFREY B · 2008 to 2012
$1.1M
NIBIB NIH HHS T32 EB005172NIGMS NIH HHS R01 GM073836
6 · The paper itself

Abstract

The last 2-3 years have seen numerous relationships develop between organometallic chemists, fluorine chemists and PET Centers around the world. These collaborations have led to the development of many new strategies for the late-stage introduction of fluorine-18 into complex bioactive molecules. In this perspective we highlight recent developments and key milestones since 2011.

Identifiers

PMID25379166
PMCPMC4217215

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.