Evidence map›Paper›PMID 25379109›Full record

ArticleBiomicrofluidics2014

Vascular smooth muscle cell culture in microfluidic devices.

Y C Wei, F Chen, T Zhang, D Y Chen, X Jia, J B Wang, W Guo, J Chen

Abstract read
In one paragraph

Article in Biomicrofluidics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Y C WeiState Key Laboratory of Transducer Technology, Institute of Electronics , Chinese Academy of Sciences, Beijing, People's Republic of China.
F ChenDepartment of Vascular Surgery, Clinical Division of Surgery, Chinese PLA General Hospital , Beijing, People's Republic of China.
T Zhang
D Y ChenState Key Laboratory of Transducer Technology, Institute of Electronics , Chinese Academy of Sciences, Beijing, People's Republic of China.
X JiaDepartment of Vascular Surgery, Clinical Division of Surgery, Chinese PLA General Hospital , Beijing, People's Republic of China.
J B WangState Key Laboratory of Transducer Technology, Institute of Electronics , Chinese Academy of Sciences, Beijing, People's Republic of China.
W GuoDepartment of Vascular Surgery, Clinical Division of Surgery, Chinese PLA General Hospital , Beijing, People's Republic of China.
J ChenState Key Laboratory of Transducer Technology, Institute of Electronics , Chinese Academy of Sciences, Beijing, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper presents a microfluidic device enabling culture of vascular smooth muscle cells (VSMCs) where extracellular matrix coating, VSMC seeding, culture, and immunostaining are demonstrated in a tubing-free manner. By optimizing droplet volume differences between inlets and outlets of micro channels, VSMCs were evenly seeded into microfluidic devices. Furthermore, the effects of extracellular matrix (e.g., collagen, poly-l-Lysine (PLL), and fibronectin) on VSMC proliferation and phenotype expression were explored. As a platform technology, this microfluidic device may function as a new VSMC culture model enabling VSMC studies.

Identifiers

PMID25379109
PMCPMC4189391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.