ArticleClinical ophthalmology (Auckland, N.Z.)2014
Bilateral endogenous Candida albicans subretinal abscess with suspected mixed bacterial infection.
Article in Clinical ophthalmology (Auckland, N.Z.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- A case of corneal abscess following self-medication with topical dermatologic corticosteroids in a child.Oxford medical case reports · 2025Article
- Subretinal abscess: causative pathogens, clinical features and management.Journal of ophthalmic inflammation and infection · 2022Review
- Article
- Sub-retinal abscess as presenting feature of endogenous Candida endophthalmitis.BMC research notes · 2018Article
- Subretinal abscess due to presumed tuberculosis in an immunocompetent young diabetic.BMJ case reports · 2016Article
- Intralesional antibiotic injection using 41G needle for the management of subretinal abscess in endogenous endophthalmitis.International journal of retina and vitreous · 2016Article
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6 authors at 2 institutions in 1 country.
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Abstract
purposeCandida albicans subretinal abscess is extremely rare. To our knowledge, only one unilateral case has been reported. Herein, we report one bilateral case. Mixed bacterial infection was also suspected based on broad-range real-time polymerase chain reaction.
methodsA 64-year-old man being treated with oral corticosteroids for interstitial pneumonia visited us for visual loss in the left eye. Best corrected visual acuity (BCVA) was 20/20 in the right eye and 8/200 in the left eye. Funduscopy revealed round yellowish-white subretinal lesions with retinal hemorrhage in both eyes.
resultsBroad-range polymerase chain reaction of the vitreous fluid from the left eye showed a high copy count of bacterial 16s ribosome RNA. Despite large doses of antibiotics, the abscess expanded and vision decreased to light perception in the left eye. Exenteration of the left eye was performed followed by microscopic examination showing Gram-negative bacilli, and C. albicans was also cultured. Antibiotics and the maximum doses of antifungal drugs were administered. However, the abscess in the right eye expanded, and BCVA decreased to 2/200. Vitrectomy and silicone oil tamponade were performed. Vitreous fluid culture revealed C. albicans. At 16 months follow-up, BCVA was stable at 4/200 with healing of the subretinal abscess under silicone oil.
conclusionSince C. albicans subretinal abscess is extremely rare and there was a concurrent mixed bacterial infection, diagnostic procedures in our bilateral case were more complicated than usual. C. albicans infection should be included in the differential diagnosis of subretinal abscesses.
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