ArticleJournal of toxicologic pathology2014
Intratubular spermatocytic seminomas in 2 sprague-dawley rats.
Article in Journal of toxicologic pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This report describes 2 cases of spontaneous intratubular spermatocytic seminomas in Sprague-Dawley rats. These rats were sacrificed at 10 weeks old (case 1) and 40 weeks old (case 2), respectively. Macroscopically, there were no remarkable changes in either case. Microscopically, tumor cells were observed within a single seminiferous tubule (case 1) or several seminiferous tubules (case 2). The proliferating tumor cells were a tripartite cell population comprising small lymphocyte-like, intermediate-sized or large-sized cells, with frequent mitoses, arranged in sheets or forming a basal layer around a tubule or tubules. Immunohistochemically, the tumor cells were strongly positive for proliferating cell nuclear antigen and weakly positive for c-kit, neuron specific enolase and VASA. Our cases provide valuable background control information for the occurrence of seminoma in rats.
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