ArticleBulletin of the World Health Organization2014
Childhood diarrhoeal deaths in seven low- and middle-income countries.
Article in Bulletin of the World Health Organization, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03870243 (Feasibility and Acceptability Followed by Effectiveness of Bubble Continuous Positive Airway Pressure), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility and Acceptability Followed by Effectiveness of Bubble Continuous Positive Airway Pressure (bCPAP) for Treatment of Children Aged 1-59 Months With Severe Pneumonia in Ethiopia: A Cluster Randomized Controlled Clinical Trial
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Place of death, care-seeking and care pathway progression in the final illnesses of children under five years of age in sub-Saharan Africa: a systematic review.Journal of global health · 2019Pooled it
- Interventions to reduce post-acute consequences of diarrheal disease in children: a systematic review.BMC public health · 2018Pooled it
- Characteristics and outcomes of children 2-23 months of age with prolonged diarrhoea: A secondary analysis of data from the 'Antibiotics for Children with Diarrhea' trial.Journal of global health · 2024Trial
- Trial
- The consequences ofEClinicalMedicine · 2026Article
- Biopsychosocial stressors and perinatal mental health: The mediating role of social support in a Pakistani cohort.Global mental health (Cambridge, England) · 2026Article
- Gut microbiota patterns associated with duration of diarrhea in children under five years of age in Ethiopia.Nature communications · 2024Article
- Article
- Article
- Effectiveness of Bubble Continuous Positive Airway Pressure (BCPAP) for Treatment of Children Aged 1-59 Months with Severe Pneumonia and Hypoxemia in Ethiopia: AJournal of clinical medicine · 2022Article
- Article
- Prevalence and epidemiological distribution of selected foodborne pathogens in human and different environmental samples in Ethiopia: a systematic review and meta-analysis.One health outlook · 2021Review
- Determinants of diarrhoeal diseases and height-for-ageJournal of preventive medicine and hygiene · 2020Article
- Quantitative Microbial Risk Assessment of Drinking Water Quality to Predict the Risk of Waterborne Diseases in Primary-School Children.International journal of environmental research and public health · 2020Article
- Glucagon-like Peptide 2 Concentrations Vary in Zambian Children During Diarrhoea, in Malnutrition and Seasonally.Journal of pediatric gastroenterology and nutrition · 2020Article
- Efficacy of a Green Banana-Mixed Diet in the Management of Persistent Diarrhea: Protocol for an Open-Labeled, Randomized Controlled Trial.JMIR research protocols · 2020Article
- Bangladesh: a success case in combating childhood diarrhoea.Journal of global health · 2019Article
- Food security is not the only solution to prevent under-nutrition among 6-59 months old children in Western Amhara region, Ethiopia.BMC pediatrics · 2019Article
- Epidemiological investigation and management of bloody diarrhea among children in India.PloS one · 2019Article
- The patient's safety and access to experimental drugs after the termination of clinical trials: regulations and trends.European journal of clinical pharmacology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
Abstract
objectiveTo investigate the clinical characteristics of children who died from diarrhoea in low- and middle-income countries, such as the duration of diarrhoea, comorbid conditions, care-seeking behaviour and oral rehydration therapy use.
methodsThe study included verbal autopsy data on children who died from diarrhoea between 2000 and 2012 at seven sites in Bangladesh, Ethiopia, Ghana, India, Pakistan, Uganda and the United Republic of Tanzania, respectively. Data came from demographic surveillance sites, randomized trials and an extended Demographic and Health Survey. The type of diarrhoea was classified as acute watery, acute bloody or persistent and risk factors were identified. Deaths in children aged 1 to 11 months and 1 to 4 years were analysed separately.
findingsThe proportion of childhood deaths due to diarrhoea varied considerably across the seven sites from less than 3% to 30%. Among children aged 1-4 years, acute watery diarrhoea accounted for 31-69% of diarrhoeal deaths, acute bloody diarrhoea for 12-28%, and persistent diarrhoea for 12-56%. Among infants aged 1-11 months, persistent diarrhoea accounted for over 30% of diarrhoeal deaths in Ethiopia, India, Pakistan, Uganda and the United Republic of Tanzania. At most sites, more than 40% of children who died from persistent diarrhoea were malnourished.
conclusionPersistent diarrhoea remains an important cause of diarrhoeal death in young children in low- and middle-income countries. Research is needed on the public health burden of persistent diarrhoea and current treatment practices to understand why children are still dying from the condition.
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