Evidence map›Paper›PMID 25378313›Full record

ArticleNucleic acids research2015

An update on LNCipedia: a database for annotated human lncRNA sequences.

Pieter-Jan Volders, Kenneth Verheggen, Gerben Menschaert, Klaas Vandepoele, Lennart Martens, Jo Vandesompele, Pieter Mestdagh

Erratum issuedAbstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 150 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

150 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
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  7. Article
  8. Article
  9. The Role of Long Intergenic Noncoding RNA in Fetal Development.International journal of molecular sciences · 2024
    Review
  10. Review
  11. Review
  12. Article
  13. Long Noncoding RNAs in Diet-Induced Metabolic Diseases.International journal of molecular sciences · 2024
    Review
  14. Recent Advances and Future Potential of Long Non-Coding RNAs in Insects.International journal of molecular sciences · 2023
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Pieter-Jan VoldersCenter for Medical Genetics, Ghent University, Ghent 9000, Belgium.
Kenneth VerheggenDepartment of Medical Protein Research, VIB, Ghent 9000, Belgium Department of Biochemistry, Ghent University, Ghent 9000 Belgium.
Gerben MenschaertDepartment of Mathematical Modelling, Statistics and Bioinformatics, Ghent University, Ghent 9000, Belgium.
Klaas VandepoeleDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Gent 9000, Belgium Department of Plant Systems Biology, VIB, Ghent 9000, Belgium.
Lennart MartensDepartment of Medical Protein Research, VIB, Ghent 9000, Belgium Department of Biochemistry, Ghent University, Ghent 9000 Belgium.
Jo VandesompeleCenter for Medical Genetics, Ghent University, Ghent 9000, Belgium.
Pieter MestdaghCenter for Medical Genetics, Ghent University, Ghent 9000, Belgium Pieter.Mestdagh@UGent.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human genome is pervasively transcribed, producing thousands of non-coding RNA transcripts. The majority of these transcripts are long non-coding RNAs (lncRNAs) and novel lncRNA genes are being identified at rapid pace. To streamline these efforts, we created LNCipedia, an online repository of lncRNA transcripts and annotation. Here, we present LNCipedia 3.0 (http://www.lncipedia.org), the latest version of the publicly available human lncRNA database. Compared to the previous version of LNCipedia, the database grew over five times in size, gaining over 90,000 new lncRNA transcripts. Assessment of the protein-coding potential of LNCipedia entries is improved with state-of-the art methods that include large-scale reprocessing of publicly available proteomics data. As a result, a high-confidence set of lncRNA transcripts with low coding potential is defined and made available for download. In addition, a tool to assess lncRNA gene conservation between human, mouse and zebrafish has been implemented.

Indexed as

Databases, Nucleic AcidAnimalsHEK293 CellsHumansInternetMiceMolecular Sequence AnnotationProteinsRNA, Long NoncodingSequence Analysis, RNAZebrafishProteinsRNA, Long Noncoding

Identifiers

PMID25378313
PMCPMC4383901

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.