ArticleBehavior genetics2015
The National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pairs genome-wide data.
Article in Behavior genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Violence against children and intimate partner violence against women: overlap and common contributing factors among caregiver-adolescent dyads.BMC public health · 2020Trial
- Adverse Childhood Experiences and Sarcopenia in Later Life: Baseline Data from the Canadian Longitudinal Study on Aging.Geriatrics (Basel, Switzerland) · 2025Article
- Article
- Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics.Behavior genetics · 2023Article
- Patterns of item nonresponse behaviour to survey questionnaires are systematic and associated with genetic loci.Nature human behaviour · 2023Article
- A Longitudinal Analysis of Gene x Environment Interaction on Verbal Intelligence Across Adolescence and Early Adulthood.Behavior genetics · 2023Article
- Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics.bioRxiv : the preprint server for biology · 2023Article
- Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.Nature neuroscience · 2021Article
- Genomic evidence consistent with antagonistic pleiotropy may help explain the evolutionary maintenance of same-sex sexual behaviour in humans.Nature human behaviour · 2021Article
- Genetic information from discordant sibling pairs points to ESRP2 as a candidate trans-acting regulator of the CF modifier gene SCNN1B.Scientific reports · 2020Article
- Genetic associations with mathematics tracking and persistence in secondary school.NPJ science of learning · 2020Article
- Cohort Profile: The National Longitudinal Study of Adolescent to Adult Health (Add Health).International journal of epidemiology · 2019Article
- Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization.International journal of epidemiology · 2019Article
- New Evidence of Skin Color Bias and Health Outcomes Using Sibling Difference Models: A Research Note.Demography · 2019Article
- Father Absence and Accelerated Reproductive Development in Non-Hispanic White Women in the United States.Demography · 2018Article
- To ERV Is Human: A Phenotype-Wide Scan Linking Polymorphic Human Endogenous Retrovirus-K Insertions to Complex Phenotypes.Frontiers in genetics · 2018Article
- Population differences in associations of serotonin transporter promoter polymorphism (5HTTLPR) di- and triallelic genotypes with blood pressure and hypertension prevalence.American heart journal · 2017Article
- Genome-Wide Estimates of Heritability for Social Demographic Outcomes.Biodemography and social biology · 2016Article
- Breastfeeding is associated with waist-to-height ratio in young adults.BMC public health · 2015Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Here we provide a detailed description of the genome-wide information available on the National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pair subsample (Harris et al. in Twin Res Hum Genet 16:391-398, 2013). A total of 2,020 samples were genotyped (including duplicates) arising from 1946 Add Health individuals from the sibling pairs subsample. After various steps for quality control (QC) and quality assurance (QA), we have high quality genome-wide data available on 1,888 individuals. In this report, we first highlight the QC and QA steps that were taken to prune the data of poorly performing samples and genetic markers. We further estimate the pairwise biological relationships using genome-wide data and compare those estimates to the assumed relationships in Add Health. Additionally, using genome-wide data from known regional reference populations from Europe, West Africa, North and South America, Japan and China, we estimate the relative genetic ancestry of the respondents. Finally, rather than conducting a traditional cross-sectional genome-wide association study (GWAS) of body mass index (BMI), we opted to utilize the extensive publicly available genome-wide information to conduct a weighted GWAS of longitudinal BMI while accounting for both family and ethnic variation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.