ArticleNature communications2014
Genomic identification and characterization of the pseudoautosomal region in highly differentiated avian sex chromosomes.
Article in Nature communications, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 52 citations in OpenAlex.
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- Elasmobranch genome sequencing reveals evolutionary trends of vertebrate karyotype organization.Genome research · 2023Article
- The evolutionary maintenance of ancient recombining sex chromosomes in the ostrich.PLoS genetics · 2023Article
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- Extreme variation in recombination rate and genetic diversity along the Sylvioidea neo-sex chromosome.Molecular ecology · 2022Article
- Genetic architecture facilitates then constrains adaptation in a host-parasite coevolutionary arms race.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Identifying the causes and consequences of assembly gaps using a multiplatform genome assembly of a bird-of-paradise.Molecular ecology resources · 2021Article
- Why Do Some Sex Chromosomes Degenerate More Slowly Than Others? The Odd Case of Ratite Sex Chromosomes.Genes · 2020Article
- Repeated sex chromosome evolution in vertebrates supported by expanded avian sex chromosomes.Proceedings. Biological sciences · 2019Article
- Evolutionary Dynamics of Sex Chromosomes of Paleognathous Birds.Genome biology and evolution · 2019Article
- Footprints of adaptive evolution revealed by whole Z chromosomes haplotypes in flycatchers.Molecular ecology · 2019Article
- Dynamic evolutionary history and gene content of sex chromosomes across diverse songbirds.Nature ecology & evolution · 2019Article
- The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes.Genome research · 2019Article
- A Genetic Map of Ostrich Z Chromosome and the Role of Inversions in Avian Sex Chromosome Evolution.Genome biology and evolution · 2018Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
The molecular characteristics of the pseudoautosomal region (PAR) of sex chromosomes remain elusive. Despite significant genome-sequencing efforts, the PAR of highly differentiated avian sex chromosomes remains to be identified. Here we use linkage analysis together with whole-genome re-sequencing to uncover the 630-kb PAR of an ecological model species, the collared flycatcher. The PAR contains 22 protein-coding genes and is GC rich. The genetic length is 64 cM in female meiosis, consistent with an obligate crossing-over event. Recombination is concentrated to a hotspot region, with an extreme rate of >700 cM/Mb in a 67-kb segment. We find no signatures of sexual antagonism and propose that sexual antagonism may have limited influence on PAR sequences when sex chromosomes are nearly fully differentiated and when a recombination hotspot region is located close to the PAR boundary. Our results demonstrate that a very small PAR suffices to ensure homologous recombination and proper segregation of sex chromosomes during meiosis.
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