Evidence map›Paper›PMID 25377344›Full record

ArticleGlobal health action2014

Disease-specific mortality burdens in a rural Gambian population using verbal autopsy, 1998-2007.

Momodou Jasseh, Stephen R C Howie, Pierre Gomez, Susana Scott, Anna Roca, Mamady Cham, Brian Greenwood, Tumani Corrah, Umberto D'Alessandro

Open access · goldAbstract read
In one paragraph

Article in Global health action, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Meteorological Factors Related to Emergency Admission of Elderly Stroke Patients in Shanghai: Analysis with a Multilayer Perceptron Neural Network.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Momodou JassehMedical Research Council, The Gambia Unit, Fajara, The Gambia; INDEPTH Network, Accra, Ghana; mjasseh@mrc.gm.
Stephen R C HowieMedical Research Council, The Gambia Unit, Fajara, The Gambia.
Pierre GomezMedical Research Council, The Gambia Unit, Fajara, The Gambia.
Susana ScottMedical Research Council, The Gambia Unit, Fajara, The Gambia; , London School of Hygiene & Tropical Medicine, London, UK.
Anna RocaMedical Research Council, The Gambia Unit, Fajara, The Gambia.
Mamady ChamAFPRC General Hospital, Farafenni, The Gambia.
Brian GreenwoodLondon School of Hygiene & Tropical Medicine, London, UK.
Tumani CorrahMedical Research Council, The Gambia Unit, Fajara, The Gambia.
Umberto D'AlessandroMedical Research Council, The Gambia Unit, Fajara, The Gambia.
MRC Unit the Gambia · GMEdward Francis Small Teaching Hospital · GMLondon School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council MC_UP_A900_1116Medical Research Council MC_UP_A900_1119Medical Research Council MC_UP_A900_1123Wellcome Trust
6 · The paper itself

Abstract

objectiveTo estimate and evaluate the cause-of-death structure and disease-specific mortality rates in a rural area of The Gambia as determined using the InterVA-4 model.

designDeaths and person-years of observation were determined by age group for the population of the Farafenni Health and Demographic Surveillance area from January 1998 to December 2007. Causes of death were determined by verbal autopsy (VA) using the InterVA-4 model and ICD-10 disease classification. Assigned causes of death were classified into six broad groups: infectious and parasitic diseases; cancers; other non-communicable diseases; neonatal; maternal; and external causes. Poisson regression was used to estimate age and disease-specific mortality rates, and likelihood ratio tests were used to determine statistical significance.

resultsA total of 3,203 deaths were recorded and VA administered for 2,275 (71%). All-age mortality declined from 15 per 1,000 person-years in 1998-2001 to 8 per 1,000 person-years in 2005-2007. Children aged 1-4 years registered the most marked (74%) decline from 27 to 7 per 1,000 person-years. Communicable diseases accounted for half (49.9%) of the deaths in all age groups, dominated by acute respiratory infections (ARI) (13.7%), malaria (12.9%) and pulmonary tuberculosis (10.2%). The leading causes of death among infants were ARI (5.59 per 1,000 person-years [95% CI: 4.38-7.15]) and malaria (4.11 per 1,000 person-years [95% CI: 3.09-5.47]). Mortality rates in children aged 1-4 years were 3.06 per 1,000 person-years (95% CI: 2.58-3.63) for malaria, and 1.05 per 1,000 person-years (95% CI: 0.79-1.41) for ARI. The HIV-related mortality rate in this age group was 1.17 per 1,000 person-years (95% CI: 0.89-1.54). Pulmonary tuberculosis and communicable diseases other than malaria, HIV/AIDS and ARI were the main killers of adults aged 15 years and over. Stroke-related mortality increased to become the leading cause of death among the elderly aged 60 years or more in 2005-2007.

conclusionsMortality in the Farafenni HDSS area was dominated by communicable diseases. Malaria and ARI were the leading causes of death in the general population. In addition to these, diarrhoeal disease was a particularly important cause of death among children under 5 years of age, as was pulmonary tuberculosis among adults aged 15 years and above.

Indexed as

Cause of DeathAdolescentAdultAgedAutopsyChildChild, PreschoolData CollectionFemaleGambiaHumansInfantInfant, NewbornMaleMiddle AgedModels, Statisticalcause of deathcommunicable diseasedisease-specific mortalityFarafennimortalitynon-communicable diseaseThe Gambiaverbal autopsy

Identifiers

PMID25377344
PMCPMC4220164
OpenAlexW1992900157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.