ArticleGlobal health action2014
Who died of what in rural KwaZulu-Natal, South Africa: a cause of death analysis using InterVA-4.
Article in Global health action, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cardiovascular disease mortality based on verbal autopsy in low- and middle-income countries: a systematic review.Bulletin of the World Health Organization · 2023Pooled it
- Trends and Clinical Characteristics of HIV and Cerebrovascular Disease in Low- and Middle-Income Countries (LMICs) Between 1990 and 2021.Current HIV/AIDS reports · 2022Pooled it
- Community-based health screening and all-cause mortality in rural South Africa: a longitudinal cohort study.BMJ public health · 2026Article
- Tuberculin skin test surveys and the Annual Risk of Tuberculous Infection in school children in Northern KwaZulu-Natal.PLOS global public health · 2024Article
- Causes and trends of adult mortality in southern Ethiopia: an eight-year follow up database study.BMC infectious diseases · 2023Article
- Space-time clustering of recently-diagnosed tuberculosis and impact of ART scale-up: Evidence from an HIV hyper-endemic rural South African population.Scientific reports · 2019Article
- Space-time patterns in maternal and mother mortality in a rural South African population with high HIV prevalence (2000-2014): results from a population-based cohort.BMC public health · 2017Article
- Tuberculosis mortality and the male survival deficit in rural South Africa: An observational community cohort study.PloS one · 2017Observational
- Article
- Passive Suicidal Ideation and Community Mental Health Resources in South Africa.Community mental health journal · 2016Article
- Cause-specific mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites.Global health action · 2014Article
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Abstract
backgroundFor public health purposes, it is important to see whether men and women in different age groups die of the same causes in South Africa.
objectiveWe explored sex- and age-specific patterns of causes of deaths in a rural demographic surveillance site in northern KwaZulu-Natal in South Africa over the period 2000-2011.
designDeaths reported through the demographic surveillance were followed up by a verbal autopsy (VA) interview using a standardised questionnaire. Causes of death were assigned likelihoods using the publicly available tool InterVA-4. Cause-specific mortality fractions were determined by age and sex.
resultsOver the study period, a total of 5,416 (47%) and 6,081 (53%) deaths were recorded in men and women, respectively. Major causes of death proportionally affecting more women than men were (all p<0.0001): human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) (20.1% vs. 13.6%), other and unspecified cardiac disease (5.9% vs. 3.2%), stroke (4.5% vs. 2.7%), reproductive neoplasms (1.7% vs. 0.4%), diabetes (2.4% vs. 1.2%), and breast neoplasms (0.4% vs. 0%). Major causes of deaths proportionally affecting more men than women were (all p<0.0001) assault (6.1% vs. 1.7%), pulmonary tuberculosis (34.5% vs. 30.2%), road traffic accidents (3.0% vs. 1.0%), intentional self-harm (1.3% vs. 0.3%), and respiratory neoplasms (2.5% vs. 1.5%). Causes of death due to communicable diseases predominated in all age groups except in older persons.
conclusionsWhile mortality during the 2000s was dominated by tuberculosis and HIV/AIDS, we found substantial sex-specific differences both for communicable and non-communicable causes of death, some which can be explained by a differing sex-specific age structure. InterVA-4 is likely to be a valuable tool for investigating causes of death patterns in other similar Southern African settings.
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