Evidence map›Paper›PMID 25376906›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2015

Perylene-diimide-based nanoparticles as highly efficient photoacoustic agents for deep brain tumor imaging in living mice.

Quli Fan, Kai Cheng, Zhen Yang, Ruiping Zhang, Min Yang, Xiang Hu, Xiaowei Ma, Lihong Bu, Xiaomei Lu, Xiaoxing Xiong and 3 more

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Review
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  9. Article
  10. Review
  11. Article
  12. Review
  13. Photoacoustics · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Quli FanKey Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Nanjing University of Posts & Telecommunications, Nanjing, 210046, China; Molecular Imaging Program at Stanford (MIPS), Canary Center at Stanford for Cancer Early Detection, Department of Radiology and Bio-X Program, School of Medicine, Stanford University, Stanford, California, 94305-5484, USA.
Kai Cheng
Zhen Yang
Ruiping Zhang
Min Yang
Xiang Hu
Xiaowei Ma
Lihong Bu
Xiaomei Lu
Xiaoxing Xiong
Wei Huang
Heng Zhao
Zhen Cheng

Funding

Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI Melinda L. Telli · 2007 to 2026
$71.4M
Stanford Nanocharacterization LaboratoryU54CA119367 · NCI · STANFORD UNIVERSITY · PI GAMBHIR, SANJIV S · 2006 to 2010
$19.8M
Small Animal ImagingP50CA114747 · NCI · STANFORD UNIVERSITY · PI RAO, JIANGHONG · 2005 to 2014
$18.2M
Pilot ProjectsU54CA151459 · NCI · STANFORD UNIVERSITY · PI GAMBHIR, SANJIV S · 2010 to 2014
$12.6M
NCI NIH HHS CA151459NCI NIH HHS P30 CA124435NCI NIH HHS P50 CA114747NCI NIH HHS U54 CA119367NCI NIH HHS U54 CA151459
6 · The paper itself

Abstract

In order to promote preclinical and clinical applications of photoacoustic imaging, novel photoacoustic contrast agents are highly desired for molecular imaging of diseases, especially for deep tumor imaging. Here, perylene-3,4,9,10-tetracarboxylic diiimide-based near-infrared-absorptive organic nanoparticles are reported as an efficient agent for photoacoustic imaging of deep brain tumors in living mice with enhanced permeability and retention effect.

Indexed as

NanoparticlesAnimalsBrain NeoplasmsCell SurvivalContrast MediaDiagnostic ImagingImidesMiceMicellesNIH 3T3 CellsPerylenePhotoacoustic TechniquesContrast MediaImidesMicellesPeryleneperylenediimidebrain tumordeep tumor imagingnear-infrared-absorptionPerylene-3,4,9,10-tetracarboxylic diimide nanoparticlesphotoacoustic imaging

Identifiers

PMID25376906
PMCPMC4347809

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.