Evidence map›Paper›PMID 25376807›Full record

ArticleAJNR. American journal of neuroradiology2015

Comparing 3T T1-weighted sequences in identifying hyperintense punctate lesions in preterm neonates.

D Tortora, V Panara, P A Mattei, A Tartaro, R Salomone, S Domizio, A R Cotroneo, M Caulo

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in AJNR. American journal of neuroradiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

D TortoraFrom the Radiology Unit (D.T., V.P., A.R.C., M.C.) ITAB-Institute of Advanced Biomedical Technologies (D.T., V.P., A.T., M.C.).
V PanaraFrom the Radiology Unit (D.T., V.P., A.R.C., M.C.) ITAB-Institute of Advanced Biomedical Technologies (D.T., V.P., A.T., M.C.).
P A MatteiOphthalmology Clinic (P.A.M.).
A TartaroFrom the Radiology Unit (D.T., V.P., A.R.C., M.C.) ITAB-Institute of Advanced Biomedical Technologies (D.T., V.P., A.T., M.C.) Department of Neuroscience and Imaging (A.T., A.R.C., M.C.), University "G. d'Annunzio" of Chieti, Chieti, Italy.
R SalomoneNeonatology and Neonatal Intensive Care Unit (R.S., S.D.), University Hospital of Chieti, Chieti, Italy.
S DomizioNeonatology and Neonatal Intensive Care Unit (R.S., S.D.), University Hospital of Chieti, Chieti, Italy.
A R CotroneoFrom the Radiology Unit (D.T., V.P., A.R.C., M.C.) Department of Neuroscience and Imaging (A.T., A.R.C., M.C.), University "G. d'Annunzio" of Chieti, Chieti, Italy.
M CauloFrom the Radiology Unit (D.T., V.P., A.R.C., M.C.) ITAB-Institute of Advanced Biomedical Technologies (D.T., V.P., A.T., M.C.) Department of Neuroscience and Imaging (A.T., A.R.C., M.C.), University "G. d'Annunzio" of Chieti, Chieti, Italy. caulo@unich.it.
Medical Technologies (Czechia) · CZUniversity of Chieti-Pescara · ITOphthalmology Clinic · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe loss of contrast on T1-weighted MR images at 3T may affect the detection of hyperintense punctate lesions indicative of periventricular leukomalacia in preterm neonates. The aim of the present study was to determine which 3T T1-weighted sequence identified the highest number of hyperintense punctate lesions and to explore the relationship between the number of hyperintense punctate lesions and clinical outcome. MATERIALS AND

methodsThe presence of hyperintense punctate lesions was retrospectively evaluated in 200 consecutive preterm neonates on 4 axial T1-weighted sequences: 3-mm inversion recovery and spin-echo and 1- and 3-mm reformatted 3D-fast-field echo. Statistically significant differences in the number of hyperintense punctate lesions were evaluated by using a linear mixed-model analysis. Logistic regression analysis was used to assess the relation between the number of hyperintense punctate lesions and neuromotor outcome at 3 months.

resultsThirty-one neonates had at least 1 hyperintense punctate lesion indicative of periventricular leukomalacia in at least 1 of the 4 sequences. The 1-mm axial reformatted 3D-fast-field echo sequence identified the greatest number of hyperintense punctate lesions (P < .001). No statistically significant differences were found among the 3-mm T1-weighted sequences. The greater number of hyperintense punctate lesions detected by the 1-mm reformatted T1 3D-fast-field echo sequence in the central region of the brain was associated with a worse clinical outcome.

conclusionsAt 3T, the 1-mm axial reformatted T1 3D-fast-field echo sequence identified the greatest number of hyperintense punctate lesions in the central region of preterm neonate brains, and this number was associated with neuromotor outcome.

Indexed as

BrainFemaleHumansInfant, NewbornInfant, PrematureLeukomalacia, PeriventricularLinear ModelsMagnetic Resonance ImagingMaleRetrospective Studies

Identifiers

PMID25376807
PMCPMC8013055
OpenAlexW2033746055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.