ArticleWorld journal of surgical oncology2014
Modular tumor endoprostheses in surgical palliation of long-bone metastases: a reduction in tumor burden and a durable reconstruction.
Article in World journal of surgical oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Longitudinal survival trends of patients with cancer with surgically managed appendicular metastatic bone disease: systematic review.Canadian journal of surgery. Journal canadien de chirurgiePooled it
- Occlusive wound closure prevents prolonged wound discharge-A randomised controlled trial in patients undergoing tumour resection and endoprosthetic reconstruction of the proximal femur because of metastatic bone disease.International wound journal · 2023Trial
- Glenohumeral Instability and Clinical Outcomes Following Proximal Humerus Resection and Megaprosthesis Implantation: A Systematic Review.Journal of clinical medicine · 2025Review
- Comparative Outcomes in Metastatic Spinal Cord Compression and Femoral Metastatic Disease: Distinct Clinical Entities with Divergent Prognoses?Medicina (Kaunas, Lithuania) · 2025Article
- Article
- Palliative care of proximal femur metastatic disease and osteolytic lesions: results following surgical and radiation treatment.BMC cancer · 2024Article
- Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report.OTA international : the open access journal of orthopaedic trauma · 2023Article
- Calcium Phosphate Cements as Carriers of Functional Substances for the Treatment of Bone Tissue.Materials (Basel, Switzerland) · 2023Review
- Application of Endoprosthetic Replacement in Old Patients with Isolated Proximal Femoral Bone Metastases.Annals of surgical oncology · 2022Article
- Cemented-augmented fixation of metastatic humeral lesions without segmental bone loss results in reliable outcomes.Annals of joint · 2022Article
- Bone cement as a local chemotherapeutic drug delivery carrier in orthopedic oncology: A review.Journal of bone oncology · 2021Review
- Oncological and functional results after surgical treatment of bone metastases at the proximal femur.BMC surgery · 2018Article
- Diagnostic algorithm, prognostic factors and surgical treatment of metastatic cancer diseases of the long bones and spine.EFORT open reviews · 2017Review
- Treatment of pathological fractures of the long bones.EFORT open reviews · 2016Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSurgical treatment of bone metastases has become increasingly important as patients live longer with metastatic cancer and one of the main aims is a long-lasting reconstruction which survives the patient. Conventional osteosynthesis may not be able to achieve this objective in the context of modern day cancer care.
methodsThis study evaluates the oncological outcomes, treatment-related complications, and function after resection of metastases and reconstruction with modular tumor endoprostheses in 80 patients. All patients who underwent surgical treatment with modular tumor prostheses for bone metastases from 1993 to 2008 were traced by our tumor database and clinical information was recorded from patient case.
resultsMean age was 63 years. The most common primary tumors were renal cell (47%), breast (21%), and lung (8%). The proximal femur was affected in 45%, proximal humerus in 26%, and the distal femur in 17% of cases. In 22 cases, the tumor prosthesis was implanted during a revision operation. Mean overall survival after surgery was 2.9 years. Overall survival rate was 70% at one year and 20% at five years. Implant survival was 83% after one year and 74% at five years. Overall rate of operative revision was 18%.
conclusionsOur data collectively suggest that despite higher costs, implantation of modular tumor endoprostheses may be a suitable treatment for bone metastases with a low complication rate and rapid improvement in function in appropriately selected patients.
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