ArticleJournal of the American Heart Association2014
Left ventricular mass and the risk of sudden cardiac death: a population-based study.
Article in Journal of the American Heart Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07270367 (Finerenone and Cardiac Remodeling), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Finerenone and Cardiac Remodeling: A Randomized, Double- Blind, Placebo-Controlled Study to Evaluate The Effects of Finerenone on Ventricular Remodeling
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Risk Prediction for Sudden Cardiac Death in the General Population: A Systematic Review and Meta-Analysis.International journal of public health · 2024Pooled it
- Interplay between PNPLA3 genotype, liver steatosis, and cardiac remodeling in young adults: A magnetic resonance imaging study.Physiological reports · 2026Article
- Increasing Left Ventricular Mass and Death in Men and Women Investigated With Echocardiography.Journal of the American Heart Association · 2025Article
- Vessel-Specific Myocardial Mass in Patients With Stable Coronary Artery Disease.Journal of the American Heart Association · 2025Article
- Loss of Elmsan1 in cardiomyocytes leads to age-dependent cardiac dysfunction and reduced lifespan.American journal of physiology. Heart and circulatory physiology · 2025Article
- Arterial stiffness in people with HIV: a cross-sectional, comparative study with echocardiographic outcomes in Tanzania.AIDS (London, England) · 2025Article
- Incidence and Progression of Diastolic Dysfunction in People With HIV in Tanzania: A Comparative Cohort.JACC. Advances · 2024Article
- Impact of Pressure Recovery Adjustment on Aortic Valve Area Classification of Disease Severity in Transcatheter Aortic Valve Replacement Patients.Journal of cardiothoracic and vascular anesthesia · 2024Observational
- Shared genetic risk between anorexia nervosa and cardiovascular disease events: Evidence from genome-wide association studies.Brain and behavior · 2024Article
- Insulin resistance/hyperinsulinemia: an important cardiovascular risk factor that has long been underestimated.Frontiers in cardiovascular medicine · 2024Article
- Multiple anthropometric measures and proarrhythmic 12-lead ECG indices: A mendelian randomization study.PLoS medicine · 2023Article
- Comparison of echocardiographic methods for calculating left ventricular mass in elite rugby football league athletes and the impact on chamber geometry.Frontiers in sports and active living · 2023Article
- Multimodality Imaging of Sudden Cardiac Death and Acute Complications in Acute Coronary Syndrome.Journal of clinical medicine · 2022Review
- Hypertension and Arrhythmias: A Clinical Overview of the Pathophysiology-Driven Management of Cardiac Arrhythmias in Hypertensive Patients.Journal of cardiovascular development and disease · 2022Review
- Recent Non-Invasive Parameters to Identify Subjects at High Risk of Sudden Cardiac Death.Journal of clinical medicine · 2022Review
- Left ventricular hypertrophy and sudden cardiac death.Heart failure reviews · 2022Review
- Plasma potassium concentration and cardiac repolarisation markers, TEuropean journal of applied physiology · 2022Article
- Arrhythmias in Chronic Kidney Disease.European cardiology · 2022Review
- The role of metabolic syndrome in sudden cardiac death risk: Recent evidence and future directions.European journal of clinical investigation · 2022Review
- Relations Between Cardiac Magnetic Resonance Imaging-Derived Left Ventricular Mass, Early Repolarization, and Cardiovascular Events (from the Dallas Heart Study).The American journal of cardiology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundLeft ventricular (LV) mass ascertained using echocardiography may enhance risk stratification for sudden cardiac death. The objective of this study was to assess the association between left ventricular mass and the risk of sudden cardiac death in a population-based cohort and determine its incremental value beyond conventional risk predictors. METHODS AND
resultsAssessment of LV mass was based on echocardiography in a sample of 905 middle-aged men representative of the general population (aged 42 to 61 years). During the follow-up period of 20 years, there were a total of 63 sudden cardiac deaths. In a comparison of the top versus the bottom quartile of LV mass adjusted by body surface area (>120 versus <89 g/m(2)), the multivariable adjusted hazard ratio was 2.57 (95% CI 1.24 to 5.31, P=0.010). Further adjustment for LV function only modestly attenuated the risk of sudden cardiac death among men with LV mass of >120 g/m(2) (hazard ratio 2.29, 95% CI 1.10 to 4.74, P=0.026). Addition of LV mass adjusted by body surface area to a conventional risk factor model for sudden cardiac death improved the integrated discrimination index by 0.033 (95% CI 0.009 to 0.057, P=0.007) and the category-free net reclassification index by 0.501 (95% CI 0.092 to 0.911, P=0.016).
conclusionsIndexed LV mass by body surface area is an independent predictor of sudden cardiac death and may help improve the risk prediction of sudden cardiac death beyond conventional cardiovascular risk factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.