ArticleAIDS research and human retroviruses2014
Seroprevalence and determinants of Kaposi sarcoma-associated human herpesvirus 8 in Indian HIV-infected males.
Article in AIDS research and human retroviruses, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- High Seroprevalence of Kaposi Sarcoma-Associated Herpesvirus in Men Who Have Sex With Men With HIV in the Southern United States.Open forum infectious diseases · 2023Article
- Kaposi's sarcoma-associated herpesvirus related malignancy in India, a rare but emerging member to be considered.Virusdisease · 2020Review
- Human herpes virus 8 antibodies in HIV-positive patients in Surabaya, Indonesia.Infectious disease reports · 2020Article
- Article
- Prevalence of HIV in Patients with Malignancy and of Malignancy in HIV Patients in a Tertiary Care Center from North India.Current HIV research · 2018Article
- HIV and cancer registry linkage identifies a substantial burden of cancers in persons with HIV in India.Medicine · 2016Article
- Viral infections associated with oral cancers and diseases in the context of HIV: a workshop report.Oral diseases · 2016Article
- Comorbidities associated with HIV and antiretroviral therapy (clinical sciences): a workshop report.Oral diseases · 2016Article
- Malignancies in human immunodeficiency virus infected patients in India: Initial experience in the HAART era.The Indian journal of medical research · 2015Article
- Seroprevalence of HSV-1 and 2 in HIV-infected males with and without GUD: Study from a tertiary care setting of India.Journal of laboratory physiciansArticle
- Disseminated Kaposi's Sarcoma in an HIV-Positive Patient: A Rare Entity in an Indian Patient.Indian journal of dermatologyArticle
- Disseminated violaceous plaques in a HIV-1-positive patient from eastern India: A manifestation of Kaposi's sarcoma.Indian journal of sexually transmitted diseases and AIDSArticle
- Human Herpesviruses as Copathogens of HIV Infection, Their Role in HIV Transmission, and Disease Progression.Journal of laboratory physiciansReview
- Kaposi's sarcoma unmasked by corticosteroids in an advanced HIV patient with tuberculosis immune reconstitution inflammatory syndrome.Indian journal of sexually transmitted diseases and AIDSArticle
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Authors and funding
4 authors.
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Abstract
In India Kaposi's sarcoma is rarely seen in AIDS patients. Hence the current belief is that the incidence of human herpesvirus-8 (HHV-8) is very low in this subcontinent, most probably due to the heterosexual route of HIV transmission. However, there is a scarcity of data on the prevalence of HHV-8 in India. In India the primary mode of HIV transmission is the heterosexual route. Therefore we aimed to determine the prevalence of antibodies against HHV-8 in North Indian HIV-infected men naive of antiretroviral therapy (ART). In a prospective study, 165 Indian adult males were recruited from an ART clinic. Blood samples were collected before administering any antiretroviral drug. The sera were tested for antibodies against HHV-8 using a commercial enzyme-linked immunosorbent assay (ELISA) kit, which detects IgG antibodies to lytic antigens of HHV-8. All positive samples were confirmed for the presence of anti-HHV-8 antibodies using an indirect immunofluorescence assay (IFA). The IFA kit is intended to detect primary, latent, persistent, or reactivated infection of HHV-8. Of the 165 males, 43 (26.06%) were positive by ELISA while 26 (15.8%) were also positive by IFA. Seroprevalence decreased with increasing age (p<0.05). Factors independently associated with HHV-8 infection were younger age group and alcohol consumption. These findings suggest that even in a heterosexual population, HHV-8 can be transmitted frequently.
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