ArticlePloS one2014
Impact of multimorbidity on disability and quality of life in the Spanish older population.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03343886 (Ageing and Health. Spanish Longitudinal Study on Ageing, Physical and Mental Health, and Its Determinants), which is not on this map. Cited by 84 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ageing and Health. Spanish Longitudinal Study on Ageing, Physical and Mental Health, and Its Determinants
Who cites it
84 citing papers in PubMed, 2 syntheses or guidelines pooled it, 179 citations in OpenAlex.
- Epidemiological features of suicidal ideation among the elderly in China based meta-analysis.BMC psychiatry · 2024Pooled it
- Pooled it
- Efficacy of a Blended Low-Intensity Internet-Delivered Psychological Program in Patients With Multimorbidity in Primary Care: Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- Longitudinal association between chronic diseases and fall risk among middle-aged and older adults in China: the mediating role of activity limitations.Journal of global health · 2026Article
- Prevalence, combination patterns, and quality of life factors of multimorbidity among older adults in southern China based on the health ecological model.Journal of global health · 2025Article
- Health and well-being of older adults in rural and urban Rwanda: epidemiological findings from a population based cross-sectional study.Journal of global health · 2025Article
- Exploring patterns of multimorbidity in South Korea using exploratory factor analysis and non negative matrix factorization.Scientific reports · 2025Article
- Multicentric Assessment of a Multimorbidity-Adjusted Disability Score to Stratify Depression-Related Risks Using Temporal Disease Maps: Instrument Validation Study.Journal of medical Internet research · 2024Article
- Predictors of basic and instrumental activities of daily living among older adults with multiple chronic conditions.BMC geriatrics · 2024Article
- Determinants of multimorbidity in older adults in Iran: a cross-sectional study using latent class analysis on the Bushehr Elderly Health (BEH) program.BMC geriatrics · 2024Article
- Prevalence of disability and associated functional limitations among older adults in Brazil.PLOS global public health · 2024Article
- Prevalence of multiple long-term chronic conditions and associated disabilities among community-dwelling adults in Riyadh.Frontiers in public health · 2024Article
- Understanding the association of disability with multimorbidity, and healthcare utilization in India's older adult population: insights from cross-sectional evidence of SAGE-2.Frontiers in public health · 2024Article
- Non-communicable diseases related multimorbidity, catastrophic health expenditure, and associated factors in Ernakulam district.Frontiers in public health · 2024Article
- Monitoring healthy ageing for the next decade: South Korea's perspective.Age and ageing · 2023Article
- The prevalence of disability and associated factors among community adults in the baseline of CHCN-BTH Cohort Study.BMC public health · 2023Article
- The Integration of Clinical Decision Support Systems Into Telemedicine for Patients With Multimorbidity in Primary Care Settings: Scoping Review.Journal of medical Internet research · 2023Article
- Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Prevalence of depression and its associated factors among stroke survivors in Saudi Arabia.Nursing open · 2023Article
- Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPopulation aging is closely related to high prevalence of chronic conditions in developed countries. In this context, health care policies aim to increase life span cost-effectively while maintaining quality of life and functional ability. There is still, however, a need for further understanding of how chronic conditions affect these health aspects. The aim of this paper is to assess the individual and combined impact of chronic physical and mental conditions on quality of life and disability in Spain, and secondly to show gender trends.
methodsCross-sectional data were collected from the COURAGE study. A total of 3,625 participants over 50 years old from Spain were included. Crude and adjusted multiple linear regressions were conducted to detect associations between individual chronic conditions and disability, and between chronic conditions and quality of life. Separate models were used to assess the influence of the number of diseases on the same variables. Additional analogous regressions were performed for males and females.
resultsAll chronic conditions except hypertension were statistically associated with poor results in quality of life and disability. Depression, anxiety and stroke were found to have the greatest impact on outcomes. The number of chronic conditions was associated with substantially lower quality of life [β for 4+ diseases: -18.10 (-20.95,-15.25)] and greater disability [β for 4+ diseases: 27.64 (24.99,30.29]. In general, women suffered from higher rates of multimorbidity and poorer results in quality of life and disability.
conclusionsChronic conditions impact greatly on quality of life and disability in the older Spanish population, especially when co-occurring diseases are added. Multimorbidity considerations should be a priority in the development of future health policies focused on quality of life and disability. Further studies would benefit from an expanded selection of diseases. Policies should also deal with gender idiosyncrasy in certain cases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.