Evidence map›Paper›PMID 25375877›Full record

ArticleJAMA ophthalmology2015

Quantitative autofluorescence as a clinical tool for expedited differential diagnosis of retinal degeneration.

Marcela Marsiglia, Winston Lee, Vinit B Mahajan, Jana Zernant, François C Delori, Stephen H Tsang, Janet R Sparrow

Abstract readCase Reports
In one paragraph

Article in JAMA ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Observational
  3. Imaging retinal melanin: a review of current technologies.Journal of biological engineering · 2018
    Review
  4. Article
  5. Article
  6. Article
  7. Fundus Autofluorescence and Clinical Applications.Journal of ophthalmic & vision research
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcela MarsigliaDepartment of Ophthalmology, Columbia University, New York, New York.
Winston LeeDepartment of Ophthalmology, Columbia University, New York, New York.
Vinit B MahajanDepartment of Ophthalmology and Visual Sciences, University of Iowa, Iowa City.
Jana ZernantDepartment of Ophthalmology, Columbia University, New York, New York.
François C DeloriSchepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts4Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
Stephen H TsangDepartment of Ophthalmology, Columbia University, New York, New York.
Janet R SparrowDepartment of Ophthalmology, Columbia University, New York, New York.

Funding

Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
Therapeutic approaches for ABCA4-associated disordersR24EY019861 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ALLIKMETS, RANDO L · 2011 to 2015
$7.2M
Toward mechanism- and gene-based therapies for retinal degenerationR01EY018213 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Stephen H Tsang · 2008 to 2026
$6.6M
Quantitative Fundus Autofluorescence in Retinal DisordersR01EY024091 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPARROW, JANET RUTHE · 2014 to 2022
$3.4M
NEI NIH HHS EY019861NEI NIH HHS EY024091NEI NIH HHS P30 EY019007NEI NIH HHS P30EY019007NEI NIH HHS R01 EY018213NEI NIH HHS R01 EY024091NEI NIH HHS R24 EY019861
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultATP-Binding Cassette TransportersDiagnosis, DifferentialDNADNA Mutational AnalysisFluorescein AngiographyFundus OculiHumansMaleMutationOptical ImagingRetinaRetinal DegenerationRetinitis PigmentosaABCA4 protein, humanATP-Binding Cassette TransportersDNA

Identifiers

PMID25375877
PMCPMC4370211

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.