Trial reportPloS one2014
Comparison of optic disc morphology of optic nerve atrophy between compressive optic neuropathy and glaucomatous optic neuropathy.
Trial report in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- Visual outcomes of sight threatening radiation-induced meningiomas after low-dose head irradiation: tinea capitis as a paradigm.Journal of neuro-oncology · 2026Article
- Longitudinal changes in optic disc cupping from the baseline in chiasmal lesion optic neuropathy and glaucoma.Scientific reports · 2024Article
- Topographic comparison of the retinal microvascular changes between patients with compressive and glaucomatous optic neuropathies.Scientific reports · 2023Article
- Automated macular segmentation can distinguish glaucomatous from compressive optic neuropathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Observational
- Differences in optic nerve head structure between acute angle-closure glaucoma and open-angle glaucoma.Scientific reports · 2023Article
- Discriminating Between Compressive Optic Neuropathy With Glaucoma-Like Cupping and Glaucomatous Optic Neuropathy Using OCT and OCTA.Translational vision science & technology · 2023Article
- Moyamoya-Like Vasculopathy and Orbital Trauma: An Association.Neuro-ophthalmology (Aeolus Press) · 2023Article
- Structural and functional differentiation between compressive and glaucomatous optic neuropathy.Scientific reports · 2022Article
- Optical Coherence Tomography Imaging of the Lamina Cribrosa: Structural Biomarkers in Nonglaucomatous Diseases.Journal of ophthalmology · 2021Review
- Bruch's Membrane Opening Minimum Rim Width in the Differential Diagnosis of Optic Neuropathies.Neuro-ophthalmology (Aeolus Press) · 2020Article
- Variable structure and function relationship of compressive optic neuropathy at the time of diagnosis.Clinical ophthalmology (Auckland, N.Z.) · 2019Article
- Crowded optic nerve head evaluation with optical coherence tomography in anterior ischemic optic neuropathy.Eye (London, England) · 2017Article
- Quantitative comparison of disc rim color in optic nerve atrophy of compressive optic neuropathy and glaucomatous optic neuropathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016Article
- Cupping in the Monkey Optic Nerve Transection Model Consists of Prelaminar Tissue Thinning in the Absence of Posterior Laminar Deformation.Investigative ophthalmology & visual science · 2016Article
- The Connective Tissue Components of Optic Nerve Head Cupping in Monkey Experimental Glaucoma Part 1: Global Change.Investigative ophthalmology & visual science · 2015Article
- A new characterization for nonarteritic anterior ischemic optic neuropathy.International journal of clinical and experimental medicine · 2015Article
- One Year of Glaucoma Research in Review-2013 to 2014.Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the optic nerve head (ONH) structure between compressive optic neuropathy (CON) and glaucomatous optic neuropathy (GON), and to determine whether selected ONH quantitative parameters effectively discriminate between GON and CON, especially CON cases presenting with a glaucoma-like disc.
methodsWe prospectively assessed 34 patients with CON, 34 age-matched patients with moderate or severe GON, and 34 age-matched healthy control subjects. The quantitative parameters of ONH structure were compared using the Heidelberg Retina Tomograph 2 (HRT2) and Spectralis optical coherence tomography with an enhanced depth imaging method.
resultsThe mean and maximum cup depths of CON were significantly smaller than those with GON (P < 0.001 and P < 0.001, respectively). The distance between Bruch's membrane opening and anterior surface of the lamina cribrosa (BMO-anterior LC) of CON was also significantly smaller than that of glaucoma but was similar to that of the healthy group (P < 0.001 and P = 0.47, respectively). Based on Moorfields regression analysis of the glaucoma classification of HRT2, 15 eyes with CON were classified with a glaucoma-like disc. The cup/disc area ratio did not differ between cases of CON with a glaucoma-like disc and cases of GON (P = 0.16), but the BMO-anterior LC and mean and maximum cup depths of CON cases with a glaucoma-like disc were smaller than those in GON (P = 0.005, P = 0.003, and P = 0.001, respectively).
conclusionsMeasurements of the cup depths and the LC depth had good ability to differentiate between CON with a glaucoma-like disc and glaucoma. There was no laminar remodeling detected by laminar surface position in the patients with CON compared to those with GON.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.