Evidence map›Paper›PMID 25375815›Full record

ArticleToxins2014

Measurement of sterigmatocystin concentrations in urine for monitoring the contamination of cattle feed.

Yasuo Fushimi, Mitsuhiro Takagi, Seiichi Uno, Emiko Kokushi, Masayuki Nakamura, Hiroshi Hasunuma, Urara Shinya, Eisaburo Deguchi, Johanna Fink-Gremmels

Open access · goldAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Toxins, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Yasuo FushimiUnited Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi 753-8515, Japan. hasu@fa3.so-net.ne.jp.
Mitsuhiro TakagiUnited Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi 753-8515, Japan. mtakagi@agri.kagoshima-u.ac.jp.
Seiichi UnoFaculty of Fisheries, Kagoshima University, Kagoshima 890-0056, Japan. uno@fish.kagoshima-u.ac.jp.
Emiko KokushiFaculty of Fisheries, Kagoshima University, Kagoshima 890-0056, Japan. kokushi@fish.kagoshima-u.ac.jp.
Masayuki NakamuraFaculty of Agriculture, Kagoshima University, Kagoshima 890-0056, Japan. masa@agri.kagoshima-u.ac.jp.
Hiroshi HasunumaShepherd Central Livestock Clinic, Kagoshima 899-1611, Japan. hasu@fa3.so-net.ne.jp.
Urara ShinyaUnited Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi 753-8515, Japan. urara@nosai-soo.com.
Eisaburo DeguchiUnited Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi 753-8515, Japan. deguchi@agri.kagoshima-u.ac.jp.
Johanna Fink-GremmelsFaculty of Veterinary Medicine, Utrecht University, Yalelaan 104, The Netherlands. J.Fink@uu.nl.
Kagoshima University · JPYamaguchi University · JPNational Livestock Breeding Center · JPUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed (1) at determining the levels of the fungal toxin sterigmatocystin (STC) in the feed and urine of cattle and (2) at evaluating the effects of supplementing the feed with a mycotoxin adsorbent (MA) on STC concentrations in urine. Two herds of female Japanese Black cattle were used in this study. The cattle in each herd were fed a standard ration containing rice straw from different sources and a standard concentrate; two groups of cattle from each herd (n = six per group) received the commercial MA, mixed with the concentrate or given as top-dressing, whereas a third group received no supplement and served as control. Urine and feed samples were collected at various time points throughout the experiment. STC concentrations were measured using liquid chromatography-tandem mass spectrometry (LC-TMS). STC concentrations in straw were higher in Herd 1 (range 0.15-0.24 mg/kg DM) than in Herd 2 (range <0.01-0.06 mg/kg DM). In Herd 1, STC concentrations in urine significantly declined 2 weeks after replacing the contaminated feed, whereas MA supplementation had no effect. In conclusion, mycotoxins in urine samples are useful biological markers for monitoring the systemic exposure of cattle to multiple mycotoxins, as well as evaluating the effectiveness of interventions.

Indexed as

AdsorptionAnimal FeedAnimal HusbandryAnimalsAnimals, Inbred StrainsAspergillus nigerBiomarkersCattleDietFemaleFood AdditivesFood ContaminationFusariumJapanLimit of DetectionOryzaBiomarkersFood AdditivesSterigmatocystin

Identifiers

PMID25375815
PMCPMC4247257
OpenAlexW2003787275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.