ArticlePeerJ2014
Noninvasive analysis of metabolic changes following nutrient input into diverse fish species, as investigated by metabolic and microbial profiling approaches.
Article in PeerJ, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Lipid-Enriched Diet Advances Early Oocyte Development in the EndangeredAnimals : an open access journal from MDPI · 2026Article
- Article
- Transcriptome analysis of the Japanese eel (Anguilla japonica) during larval metamorphosis.BMC genomics · 2024Article
- Microbiome and Metabolome Analyses in Different Closed-Circulation Aquarium Systems and Their Network Visualization.ACS omega · 2022Article
- The exposome paradigm to predict environmental health in terms of systemic homeostasis and resource balance based on NMR data science.RSC advances · 2021Review
- Microbiome Composition and Function in Aquatic Vertebrates: Small Organisms Making Big Impacts on Aquatic Animal Health.Frontiers in microbiology · 2021Review
- Putative imbalanced amino acid metabolism in rainbow trout long term fed a plant-based diet as revealed byJournal of nutritional science · 2021Article
- Large-Scale Evaluation of Major Soluble Macromolecular Components of Fish Muscle from a ConventionalMolecules (Basel, Switzerland) · 2020Article
- Integrative Metabolomics for Assessing the Effect of Insect (Metabolites · 2020Article
- Systemic Homeostasis in Metabolome, Ionome, and Microbiome of Wild Yellowfin Goby in Estuarine Ecosystem.Scientific reports · 2018Article
- Application of kernel principal component analysis and computational machine learning to exploration of metabolites strongly associated with diet.Scientific reports · 2018Article
- Composition of Intestinal Microbiota in Two Lines of Rainbow Trout (The open microbiology journal · 2018Article
- Intestinal microbiota composition is altered according to nutritional biorhythms in the leopard coral grouper (Plectropomus leopardus).PloS one · 2018Article
- Trans-omics approaches used to characterise fish nutritional biorhythms in leopard coral grouper (Plectropomus leopardus).Scientific reports · 2017Article
- Article
- Visualization of Microfloral Metabolism for Marine Waste Recycling.Metabolites · 2016Article
- Identification of Reliable Components in Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS): a Data-Driven Approach across Metabolic Processes.Scientific reports · 2015Article
- Selective Manipulation of the Gut Microbiota Improves Immune Status in Vertebrates.Frontiers in immunology · 2015Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An NMR-based metabolomic approach in aquatic ecosystems is valuable for studying the environmental effects of pharmaceuticals and other chemicals on fish. This technique has also contributed to new information in numerous research areas, such as basic physiology and development, disease, and water pollution. We evaluated the microbial diversity in various fish species collected from Japan's coastal waters using next-generation sequencing, followed by evaluation of the effects of feed type on co-metabolic modulations in fish-microbial symbiotic ecosystems in laboratory-scale experiments. Intestinal bacteria of fish in their natural environment were characterized (using 16S rRNA genes) for trophic level using pyrosequencing and noninvasive sampling procedures developed to study the metabolism of intestinal symbiotic ecosystems in fish reared in their environment. Metabolites in feces were compared, and intestinal contents and feed were annotated based on HSQC and TOCSY using SpinAssign and network analysis. Feces were characterized by species and varied greatly depending on the feeding types. In addition, feces samples demonstrated a response to changes in the time series of feeding. The potential of this approach as a non-invasive inspection technique in aquaculture is suggested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.