ArticleFacts, views & vision in ObGyn2014
The potential of letrozole use for priming in vitro maturation cycles.
Article in Facts, views & vision in ObGyn, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04149496 (A Prospective Series of IVF Cases Utilizing in Vitro Maturation), which is not on this map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective Series of IVF Cases Utilizing in Vitro Maturation (IVM) With Low Cost Priming, Enhanced Oocyte Recovery, and Delayed Embryo Transfer Using a Subsequent Frozen Embryo Transfer Cycle
Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- The letrozole use in reproductive medicine: Beyond aromatase inhibition - a comprehensive review.Turkish journal of obstetrics and gynecology · 2026Article
- Review
- Unraveling the Puzzle: Oocyte Maturation Abnormalities (OMAS).Diagnostics (Basel, Switzerland) · 2022Review
- Oocyte maturation abnormalities - A systematic review of the evidence and mechanisms in a rare but difficult to manage fertility pheneomina.Turkish journal of obstetrics and gynecology · 2022Article
- Letrozole for Female Infertility.Frontiers in endocrinology · 2021Review
- A review of the physiology behind letrozole applications in infertility: are current protocols optimal?Journal of assisted reproduction and genetics · 2020Review
- A comparison of the use of clomiphene citrate and letrozole in patients undergoing IVF with the objective of producing only one or two embryos.Facts, views & vision in ObGyn · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the pregnancy rates with two different methods of priming for in vitro maturation cycles (IVM). Cycles using letrozole together with hCG were compared to cycles using FSH together with hCG in 75 cycles in patients being treated for infertility by IVM. STUDY
designRetrospective cohort non-inferiority trial Results: Using letrozole for priming was found to not be inferior to using FSH for priming cycles. The live birth rate per transfer was 31.6% in letrozole primed cycles compared to 20.8% in FSH primed cycles (not significant). However, FSH priming produced more oocytes that were mature on the day of retrieval (p = 0.004) and also resulted in more high quality embryos than did letrozole priming (p = 0.004).
conclusionLetrozole may be used for priming in IVM cycles in which the clinician views the characteristics of letrozole as more desirable than FSH.
Indexed as
Identifiers
25374658PMC4216981W262299558What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.