Evidence map›Paper›PMID 25374515›Full record

ReviewFrontiers in integrative neuroscience2014

Rehabilitation of homonymous hemianopia: insight into blindsight.

Céline Perez, Sylvie Chokron

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Frontiers in integrative neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04021160 (The Efficacy of Navigated Perilesional Repetitive Transcranial Magnetic Stimulation on Post-Stroke Visual Field Defects), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04021160 nacompletednot on this mapstarted 2018, after this paper: background citation

The Efficacy of Navigated Perilesional Repetitive Transcranial Magnetic Stimulation on Post-Stroke Visual Field Defects

TypeinterventionalSponsorAin Shams UniversityRan2018 to 2020Enrolled32ConditionsVisual Fields Hemianopsia, Stroke, Ischemic, Stroke HemorrhagicArmsHigh frequency repetitive transcranial magnetic stimulation (rTMS), Sham stimulation
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  16. The superior colliculus is sensitive to gestalt-like stimulus configuration in hemispherectomy patients.Cortex; a journal devoted to the study of the nervous system and behavior · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Céline PerezNeurology, Unité Fonctionnelle Vision et Cognition, Fondation Ophtalmologique Rothschild Paris, France.
Sylvie ChokronNeurology, Unité Fonctionnelle Vision et Cognition, Fondation Ophtalmologique Rothschild Paris, France ; Laboratoire de Psychologie de la Perception, Université Paris-Descartes, UMR 8242 CNRS Paris, France.
Centre National de la Recherche Scientifique · FRFondation Ophtalmologique Adolphe de Rothschild · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strong evidence of considerable plasticity in primary sensory areas in the adult cortex, and of dramatic cross-modal reorganization in visual areas, after short- or long-term visual deprivation has recently been reported. In the context of patient rehabilitation, this scientifically challenging topic takes on urgent clinical relevance, especially given the lack of information about the role of such reorganization on spared or newly emerged visual performance. Amongst the most common visual field defects found upon unilateral occipital damage of the primary visual cortex is homonymous hemianopia (HH), a perfectly symmetric loss of vision in both eyes. Traditionally, geniculostriate lesions were considered to result in complete and permanent visual loss in the topographically related area of the visual field (Huber, 1992). However, numerous studies in monkeys, and later, in humans, have demonstrated that despite destruction of the striate cortex, or even following a hemispherectomy, some patients retain a certain degree of unconscious visual function, known as blindsight. Accordingly, there have recently been attempts to restore visual function in patients by stimulating unconscious preserved blindsight capacities. Herein we review different visual rehabilitation techniques designed for brain-damaged patients with visual field loss. We discuss the hypothesis that explicit (conscious) visual detection can be restored in the blind visual field by harnessing implicit (unconscious) visual capacities. The results that we summarize here underline the need for early diagnosis of cortical visual impairment (CVI), and the urgency in rehabilitating such deficits, in these patients. Based on the research precedent, we explore the link between implicit (unconscious) vision and conscious perception and discuss possible mechanisms of adaptation and plasticity in the visual cortex.

Indexed as

blindsightbrain reorganizationcortical visual impairmenthomonymous hemianopiaplasticitypost-chiasmatic damagerehabilitation

Identifiers

PMID25374515
PMCPMC4206079
OpenAlexW2093294789

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.