Evidence map›Paper›PMID 25374297›Full record

ReviewCellular and molecular life sciences : CMLS2015

Bacterial chemoreceptors and chemoeffectors.

Shuangyu Bi, Luhua Lai

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. ZnbioRxiv : the preprint server for biology · 2026
    Article
  2. Structure and signaling mechanism ofbioRxiv : the preprint server for biology · 2026
    Article
  3. Sigma B regulated motility and chemotaxis inMicrobiology (Reading, England) · 2026
    Article
  4. Article
  5. Review
  6. Insights into Chemoreceptor MCP2201-Sensing D-Malate.International journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Only Chemoreceptor Encoded byMicroorganisms · 2021
    Article
  13. The Divergent Key Residues of TwoMicroorganisms · 2021
    Article
  14. Article
  15. Microbial genomics · 2020
    Article
  16. Article
  17. Article
  18. Genetic factors involved in rhizosphere colonization by phytobeneficialComputational and structural biotechnology journal · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shuangyu BiCenter for Quantitative Biology, Peking University, Beijing, 100871, China.
Luhua Lai

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria use chemotaxis signaling pathways to sense environmental changes. Escherichia coli chemotaxis system represents an ideal model that illustrates fundamental principles of biological signaling processes. Chemoreceptors are crucial signaling proteins that mediate taxis toward a wide range of chemoeffectors. Recently, in deep study of the biochemical and structural features of chemoreceptors, the organization of higher-order clusters in native cells, and the signal transduction mechanisms related to the on-off signal output provides us with general insights to understand how chemotaxis performs high sensitivity, precise adaptation, signal amplification, and wide dynamic range. Along with the increasing knowledge, bacterial chemoreceptors can be engineered to sense novel chemoeffectors, which has extensive applications in therapeutics and industry. Here we mainly review recent advances in the E. coli chemotaxis system involving structure and organization of chemoreceptors, discovery, design, and characterization of chemoeffectors, and signal recognition and transduction mechanisms. Possible strategies for changing the specificity of bacterial chemoreceptors to sense novel chemoeffectors are also discussed.

Indexed as

Chemoreceptor CellsChemotaxisDirected Molecular EvolutionEscherichia coliEscherichia coli ProteinsSignal TransductionEscherichia coli Proteins

Identifiers

PMID25374297
PMCPMC11113376

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.