ArticleInternational urology and nephrology2015
Comparison of estimated GFR and measured GFR in prospective living kidney donors.
Article in International urology and nephrology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Review
- Comparison of Three Glomerular Filtration Rate Estimating Equations with 24-Hour Urine Creatinine Clearance Measurement in Potential Living Kidney Donors.International journal of nephrology · 2023Article
- Evaluating the Impact and Rationale of Race-Specific Estimations of Kidney Function: Estimations from U.S. NHANES, 2015-2018.EClinicalMedicine · 2021Article
- Assessing Renal Function for Kidney Donation. How Low Is Too Low?Frontiers in medicine · 2021Review
- Increased Glomerular Filtration Rate in Early Stage of Balkan Endemic Nephropathy.Medicina (Kaunas, Lithuania) · 2019Article
- [Applying the simplified modification of diet in renal disease and the chronic kidney disease epidemiology collaboration equation for evaluation of glomerular filtration rate in patients with decompensated liver cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019Article
- Baseline living-donor kidney volume and function associate with 1-year post-nephrectomy kidney function.Clinical transplantation · 2019Article
- Renal and cardiac assessment of living kidney donor candidates.Nature reviews. Nephrology · 2017Review
- Comparison of Different Equations with GFR Measured by Scintigraphy in Kidney Donors.Indian journal of nephrologyArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to examine the usefulness of three GFR-estimating equations (eGFR) compared with measured GFR (mGFR) in potential living kidney donors.
methodsWe compared the performance of the MDRD, CKD-Epi and Cockcroft-Gault equations with mGFR measured using (51)Cr-EDTA in 508 consecutive potential living kidney donors. Each equation was assessed for bias, precision and accuracy compared with mGFR, and the sensitivity and specificity for the identification of donors with mGFR<80 mL/min/1.73 m2 was evaluated.
resultsTwo hundred and forty-four subjects were male, 398 Caucasian, 60 Afro-Caribbean and 50 from other ethnic groups. Median age and mGFR were 44.1 year and 91.7 mL/min/1.73 m2, respectively. Spearman correlation coefficients between eGFR and mGFR were in the range R s=0.520-0.593. Median bias (eGFR-mGFR) for the MDRD, CKD-Epi and Cockcroft-Gault equations were -1.0 (p=0.98), +8.8 (p<0.0001) and +11.1 (p<0.0001) mL/min/1.73 m2, respectively. Significant differences in bias between Afro-Caribbean and Caucasian subjects were found. The sensitivity (specificity) for the MDRD, CKD-Epi and Cockcroft-Gault equations for identifying subjects with mGFR<80 mL/min/1.73 m2 was 60 (83), 39 (95) and 44% (95%), respectively.
conclusionsThe level of agreement between mGFR and all three eGFR values was poor, with the MDRD equation performing best. We conclude that reliance on creatinine-based eGFR values is unsatisfactory for the evaluation of potential living kidney donors.
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