Evidence map›Paper›PMID 25373970›Full record

ArticleThe Journal of the Acoustical Society of America2014

Otoacoustic-emission-based medial-olivocochlear reflex assays for humans.

Lynne Marshall, Judi A Lapsley Miller, John J Guinan, Christopher A Shera, Charlotte M Reed, Zachary D Perez, Lorraine A Delhorne, Paul Boege

Abstract read
In one paragraph

Article in The Journal of the Acoustical Society of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Differentiating Middle Ear and Medial Olivocochlear Effects on Transient-Evoked Otoacoustic Emissions.Journal of the Association for Research in Otolaryngology : JARO · 2017
    Trial
  2. Electrocochleographic Changes Predict an Early Sign of Cochlear Degeneration.World journal of otorhinolaryngology - head and neck surgery · 2026
    Article
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  7. Auditory Deprivation during Development Alters Efferent Neural Feedback and Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lynne MarshallNaval Submarine Medical Research Laboratory, Box 900, Subase NLON, Box 900, Groton, Connecticut 06349-5900.
Judi A Lapsley MillerNaval Submarine Medical Research Laboratory, Box 900, Subase NLON, Box 900, Groton, Connecticut 06349-5900.
John J GuinanEaton-Peabody Laboratory of Auditory Physiology, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, Massachusetts 02114.
Christopher A SheraEaton-Peabody Laboratory of Auditory Physiology, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, Massachusetts 02114.
Charlotte M ReedResearch Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139-4307.
Zachary D PerezResearch Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139-4307.
Lorraine A DelhorneResearch Laboratory of Electronics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139-4307.
Paul BoegeConsultant, Hirschanger 17, D-82319, Starnberg, Germany.

Funding

UNDERSTANDING OTOACOUSTIC EMISSIONSR01DC003687 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christopher A Shera · 1999 to 2026
$9.8M
6 · The paper itself

Abstract

Otoacoustic emission (OAE) tests of the medial-olivocochlear reflex (MOCR) in humans were assessed for viability as clinical assays. Two reflection-source OAEs [TEOAEs: transient-evoked otoacoustic emissions evoked by a 47 dB sound pressure level (SPL) chirp; and discrete-tone SFOAEs: stimulus-frequency otoacoustic emissions evoked by 40 dB SPL tones, and assessed with a 60 dB SPL suppressor] were compared in 27 normal-hearing adults. The MOCR elicitor was a 60 dB SPL contralateral broadband noise. An estimate of MOCR strength, MOCR%, was defined as the vector difference between OAEs measured with and without the elicitor, normalized by OAE magnitude (without elicitor). An MOCR was reliably detected in most ears. Within subjects, MOCR strength was correlated across frequency bands and across OAE type. The ratio of across-subject variability to within-subject variability ranged from 2 to 15, with wideband TEOAEs and averaged SFOAEs giving the highest ratios. MOCR strength in individual ears was reliably classified into low, normal, and high groups. SFOAEs using 1.5 to 2 kHz tones and TEOAEs in the 0.5 to 2.5 kHz band gave the best statistical results. TEOAEs had more clinical advantages. Both assays could be made faster for clinical applications, such as screening for individual susceptibility to acoustic trauma in a hearing-conservation program.

Indexed as

Acoustic Impedance TestsAdolescentAdultAudiometryAuditory ThresholdCochleaDisease SusceptibilityEfferent PathwaysFemaleHair Cells, Auditory, OuterHearing Loss, Noise-InducedHumansMaleOtoacoustic Emissions, SpontaneousReflexReproducibility of Results

Identifiers

PMID25373970
PMCPMC5392105

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.