ArticleCell reports2014
Mechanosensitive neurons on the internal reproductive tract contribute to egg-laying-induced acetic acid attraction in Drosophila.
Article in Cell reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed, 87 citations in OpenAlex.
- Article
- The TRP-channel painless mediates substrate stiffness sensing in the legs during Drosophila oviposition.PLoS genetics · 2025Article
- Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons.eLife · 2024Article
- Transsynaptic BMP Signaling Regulates Fine-Scale Topography between Adjacent Sensory Neurons.eNeuro · 2024Article
- Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons.bioRxiv : the preprint server for biology · 2024Article
- Expression and potential regulatory functions of Drosophila octopamine receptors in the female reproductive tract.G3 (Bethesda, Md.) · 2024Article
- Finishing the egg.Genetics · 2024Article
- Heterogeneity in the projections and excitability of tyraminergic/octopaminergic neurons that innervate theFrontiers in molecular neuroscience · 2024Article
- Article
- Neuronal substrates of egg-laying behaviour at the abdominal ganglion of Drosophila melanogaster.Scientific reports · 2023Article
- Glia instruct axon regeneration via a ternary modulation of neuronal calcium channels in Drosophila.Nature communications · 2023Article
- Muscle-directed mechanosensory feedback activates egg-laying circuit activity and behavior in Caenorhabditis elegans.Current biology : CB · 2023Article
- Flexible neural control of transition points within the egg-laying behavioral sequence in Drosophila.Nature neuroscience · 2023Article
- Gliotransmission and adenosine signaling promote axon regeneration.Developmental cell · 2023Article
- A dopamine-gated learning circuit underpins reproductive state-dependent odor preference ineLife · 2022Article
- Regulation ofiScience · 2022Article
- Mutualism promotes insect fitness by fungal nutrient compensation and facilitates fungus propagation by mediating insect oviposition preference.The ISME journal · 2022Article
- A functional division ofProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Drosophila females receive male substrate-borne signals through specific leg neurons during courtship.Current biology : CB · 2021Article
- Behavioral and Genomic Sensory Adaptations Underlying the Pest Activity of Drosophila suzukii.Molecular biology and evolution · 2021Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Selecting a suitable site to deposit their eggs is an important reproductive need of Drosophila females. Although their choosiness toward egg-laying sites is well documented, the specific neural mechanism that activates females' search for attractive egg-laying sites is not known. Here, we show that distention and contraction of females' internal reproductive tract triggered by egg delivery through the tract plays a critical role in activating such search. We found that females start to exhibit acetic acid (AA) attraction prior to depositing each egg but no attraction when they are not laying eggs. Artificially distending the reproductive tract triggers AA attraction in non-egg-laying females, whereas silencing the mechanosensitive neurons we identified that can sense the contractile status of the tract eliminates such attraction. Our work uncovers the circuit basis of an important reproductive need of Drosophila females and provides a simple model for dissecting the neural mechanism that underlies a reproductive need-induced behavioral modification.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.