Evidence map›Paper›PMID 25373382›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2015

Analyses of drugs stored at home by elderly patients with chronic heart failure.

Sebastian Ewen, Tanja Baumgarten, Volker Rettig-Ewen, Felix Mahfoud, Nina Griese-Mammen, Martin Schulz, Michael Böhm, Ulrich Laufs

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Evaluating patients' comprehensibility of a standardized medication plan.European journal of clinical pharmacology · 2016
    Article
  13. Heart failure and the holidays.Clinical research in cardiology : official journal of the German Cardiac Society · 2016
    Article
  14. Atorvastatin treatment and LDL cholesterol target attainment in patients at very high cardiovascular risk.Clinical research in cardiology : official journal of the German Cardiac Society · 2016
    Article
  15. General practitioners' adherence to chronic heart failure guidelines regarding medication: the GP-HF study.Clinical research in cardiology : official journal of the German Cardiac Society · 2016
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sebastian EwenKlinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrberger Str., Geb. 40, 66421, Homburg/Saar, Germany, sebastian.ewen@uks.eu.
Tanja Baumgarten
Volker Rettig-Ewen
Felix Mahfoud
Nina Griese-Mammen
Martin Schulz
Michael Böhm
Ulrich Laufs
Universitätsklinikum des Saarlandes · DEFederal Union of German Associations of Pharmacists · DESchott (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEvidence-based pharmacotherapy improves morbidity and mortality in patients with chronic heart failure (CHF). Medication adherence management is important for the effectiveness and safety of treatment. This study investigated drugs stored at home by elderly CHF patients. METHODS AND

resultsOne hundred and one patients with stable CHF age ≥65 years were visited at home where a standardized interview and a thorough assessment of medication were performed. Mean age of the patients was 77.7 ± 6.1 years, 53 % male, mean NYHA functional class of 2.8 ± 0.7 and a Minnesota-Living-with-Heart-Failure score of 59.4 ± 28.6 points indicating reduced quality of life. The mean number of different drug packs per patient was 13.1 ± 5.5, corresponding to a mean indexed value per patient of <euro>403 ± 48. Cardiovascular drugs accounted for 32 % of the packs. On average, 2.4 ± 3.2 packs contained medication that was not taken by the patient (18 % of the medication, mean indexed value <euro>61 ± 8). Fifty-six percent of the unused drugs were prescribed by general practitioners, 23 % in the hospital, and 7 % by medical specialists and 14 % were over-the-counter drugs. Sixty-three packages (5 %) of the drugs at home were expired (mean indexed value per patient <euro>12 ± 3).

conclusionOn average, elderly patients with CHF have to manage 13 different drug packs per day at home of which a significant portion is not taken as prescribed. New strategies are needed to support medicines management at home.

Indexed as

Drug MonitoringPolypharmacyCardiovascular AgentsChronic DiseaseFemaleGermanyHeart FailureHumansMaleMiddle AgedNonprescription DrugsSelf MedicationCardiovascular AgentsNonprescription Drugs

Identifiers

PMID25373382
OpenAlexW2148788591

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.