ReviewSurgery today2015
Incidence and prognostic significance of positive peritoneal lavage in colorectal cancer.
Review in Surgery today, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Impact of the number of colorectal cancer lymph node metastases on intraperitoneal lavage cytology: a multi-institutional, prospective, observational study.Surgery today · 2026Observational
- Peritoneal Lavage Cytology Predicts Peritoneal Metastasis and is Associated with Poor Prognosis in Patients with Stage II-III Colorectal Cancer.Annals of surgical oncology · 2025Article
- Article
- Investigation of Peritoneal Lavage Cytology before and after Tumor Resection as a Prognostic Factor in Colorectal Cancer.Journal of the anus, rectum and colon · 2025Article
- Oncologic Impact of Conservative Treatment Compared with Surgical Treatment of Anastomotic Leakage Following Colorectal Cancer Surgery: A Retrospective Study.Journal of the anus, rectum and colon · 2025Article
- Prognostic Impact of Potentially Curative Resection for Synchronous Peritoneal Carcinomatosis with Lavage Cytology Positivity in Colorectal Cancer: A Retrospective Observational Study.Journal of the anus, rectum and colon · 2025Article
- Exfoliate cancer cell analysis in rectal cancer surgery: comparison of laparoscopic and transanal total mesorectal excision, a pilot study.Annals of coloproctology · 2023Article
- Comparison of prognostic impact between positive intraoperative peritoneal and lavage cytologies in colorectal cancer.International journal of clinical oncology · 2021Article
- Interleukin 10 level in the peritoneal cavity is a prognostic marker for peritoneal recurrence of T4 colorectal cancer.Scientific reports · 2021Article
- Conventional peritoneal cytology lacks the prognostic significance of detecting local or peritoneal recurrence in colorectal cancer: An Egyptian experience.JGH open : an open access journal of gastroenterology and hepatology · 2021Article
- Role of Peritoneal Cytology in Patients with Early Stage Colorectal Cancer.Pathology oncology research : POR · 2020Article
- Article
- Metastatic Colorectal Cancer to the Peritoneum: Current Treatment Options.Current treatment options in oncology · 2018Review
- Clinical significance of carcinoembryonic antigen in peritoneal fluid detected during operation in stage I-III colorectal cancer patients.Intestinal research · 2018Article
- Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) delivered via a modified perfusion system for peritoneal carcinomatosis of colorectal origin.Surgery today · 2016Article
- Intraoperative peritoneal lavage: limitations of current evidence for clinical implementation.Annals of coloproctology · 2014Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe significance of peritoneal lavage cytology as a prognostic marker has been examined in various types of cancer. However, the meaning of positive peritoneal lavage cytology in colorectal cancer is still controversial. The aim of this review is to evaluate the prognostic significance of positive peritoneal lavage cytology in colorectal cancer.
methodsAn English literature search was performed on all studies published between 1998 and 2014 that compared the detection of peritoneal free cancer cells with survival or recurrence.
resultsEighteen articles met the inclusion criteria. All studies employed one (or more) of the three techniques used to detect free cancer cells in the peritoneal cavity: (1) conventional cytology, (2) immunocytochemistry or (3) polymerase chain reaction. The incidence of positive peritoneal lavage cytology ranged from 2.2 to 47.2% across the studies. The factors correlated with positive peritoneal lavage cytology were tumor penetration and metastases (lymph node, liver and peritoneum). In nine studies, positive lavage findings were associated with a worse survival, and it was associated with increased recurrence in 13 studies.
conclusionPositive peritoneal lavage cytology seems to be an indicator of a poor prognosis in colorectal cancer patients. Further studies are needed to clarify the prognostic impact of peritoneal lavage cytology, by comparing the different methods used for the collection of the peritoneal lavage.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.