Evidence map›Paper›PMID 25372607›Full record

ArticlePloS one2014

Multilayered polyelectrolyte microcapsules: interaction with the enzyme cytochrome C oxidase.

Laura Pastorino, Elena Dellacasa, Mohamed R Noor, Tewfik Soulimane, Paolo Bianchini, Francesca D'Autilia, Alexei Antipov, Alberto Diaspro, Syed A M Tofail, Carmelina Ruggiero

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Laura PastorinoDepartment of Informatics, Bioengineering, Robotics and Systems Engineering, University of Genova, Genova, Italy.
Elena DellacasaDepartment of Informatics, Bioengineering, Robotics and Systems Engineering, University of Genova, Genova, Italy.
Mohamed R NoorDepartment of Chemical and Environmental Sciences, University of Limerick, Limerick, Ireland; Materials and Surface Science Institute, University of Limerick, Limerick, Ireland.
Tewfik SoulimaneDepartment of Chemical and Environmental Sciences, University of Limerick, Limerick, Ireland; Materials and Surface Science Institute, University of Limerick, Limerick, Ireland.
Paolo BianchiniNanophysics, Istituto Italiano di Tecnologia, Genova, Italy.
Francesca D'AutiliaNanophysics, Istituto Italiano di Tecnologia, Genova, Italy.
Alexei AntipovPlasmaChem GmbH, Berlin, Germany.
Alberto DiasproNanophysics, Istituto Italiano di Tecnologia, Genova, Italy.
Syed A M TofailMaterials and Surface Science Institute, University of Limerick, Limerick, Ireland.
Carmelina RuggieroDepartment of Informatics, Bioengineering, Robotics and Systems Engineering, University of Genova, Genova, Italy.
Italian Institute of Technology · ITUniversity of Genoa · ITUniversity of Limerick · IEPlasmaChem (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-sized polyelectrolyte capsules functionalized with a redox-driven proton pump protein were assembled for the first time. The interaction of polyelectrolyte microcapsules, fabricated by electrostatic layer-by-layer assembly, with cytochrome c oxidase molecules was investigated. We found that the cytochrome c oxidase retained its functionality, that the functionalized microcapsules interacting with cytochrome c oxidase were permeable and that the permeability characteristics of the microcapsule shell depend on the shell components. This work provides a significant input towards the fabrication of an integrated device made of biological components and based on specific biomolecular functions and properties.

Indexed as

Bacterial ProteinsCapsulesElectron Transport Complex IVEnzymes, ImmobilizedThermus thermophilusBacterial ProteinsCapsulesElectron Transport Complex IVEnzymes, Immobilized

Identifiers

PMID25372607
PMCPMC4221607
OpenAlexW2029948832

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.