ArticleArquivos brasileiros de cardiologia2015
Use of short-term circulatory support as a bridge in pediatric heart transplantation.
Article in Arquivos brasileiros de cardiologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- Clinical Outcome of Heart Transplantation in Children and Young Adults with Congenital and Acquired Heart Disease in a Middle-Income Country: A 20-Year Experience from a Single Center in Brazil.Brazilian journal of cardiovascular surgery · 2025Article
- The Influence of Social Determinants of Health on the Survival of Heart Transplants in the Pediatric Age: An Analysis of a Mexican Cohort and Its Comparison with Latin America and the Caribbean.Journal of clinical medicine · 2025Article
- Circulatory Support as a Bridge to Pediatric Heart Transplantation.Arquivos brasileiros de cardiologia · 2016Article
- Rational Use of Mechanical Circulatory Support as a Bridge to Pediatric and Congenital Heart Transplantation.Brazilian journal of cardiovascular surgeryArticle
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHeart transplantation is considered the gold standard therapy for the advanced heart failure, but donor shortage, especially in pediatric patients, is the main limitation for this procedure, so most sick patients die while waiting for the procedure.
objectiveTo evaluate the use of short-term circulatory support as a bridge to transplantation in end-stage cardiomyopathy.
methodsRetrospective clinical study. Between January 2011 and December 2013, 40 patients with cardiomyopathy were admitted in our Pediatric Intensive Care Unit, with a mean age of 4.5 years. Twenty patients evolved during hospitalization with clinical deterioration and were classified as Intermacs 1 and 2. One patient died within 24 hours and 19 could be stabilized and were listed. They were divided into 2 groups: A, clinical support alone and B, implantation of short-term circulatory support as bridge to transplantation additionally to clinical therapy.
resultsWe used short-term mechanical circulatory support as a bridge to transplantation in 9. In group A (n=10), eight died waiting and 2 patients (20%) were transplanted, but none was discharged. In group B (n=9), 6 patients (66.7%) were transplanted and three were discharged.The mean support time was 21,8 days (6 to 984 h). The mean transplant waiting list time was 33,8 days. Renal failure and sepsis were the main complication and cause of death in group A while neurologic complications were more prevalent en group B.
conclusionMechanical circulatory support increases survival on the pediatric heart transplantation waiting list in patients classified as Intermacs 1 and 2.
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