ReviewPediatric exercise science2014
Exercise, hormones and skeletal adaptations during childhood and adolescence.
Review in Pediatric exercise science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Comprehensive exercise recommendations for pediatric asthma: an evidence synthesis.World journal of pediatrics : WJP · 2026Pooled it
- Taekwondo Training Improves Mood and Sociability in Children from Multicultural Families in South Korea: A Randomized Controlled Pilot Study.International journal of environmental research and public health · 2018Trial
- Fibrous dysplasia: clinical and pathologic characteristics, surgical approaches, and outcomes in a large Italian cohort.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Article
- Sex- and Age-Specific Associations Between Visceral Fat-to-Muscle Ratio and Bone Mineral Density in Children and Adolescents.International journal of endocrinology · 2026Article
- The Crucial Role of Exercise in Promoting Adolescent Bone Health.Advances in experimental medicine and biology · 2026Review
- Sarcopenic obesity and skeletal development in children: recent advances.Frontiers in pediatrics · 2026Review
- Factors associated with bone health in long distance runners: a cross-sectional study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- Article
- Evaluating and optimizing bone health in children with chronic health conditions.Paediatrics & child health · 2022Article
- L'évaluation et l'optimisation de la santé osseuse chez les enfants ayant des affections chroniques.Paediatrics & child health · 2022Article
- Associations between match participation, maturation, physical fitness, and hormonal levels in elite male soccer player U15: a prospective study with observational cohort.BMC pediatrics · 2022Observational
- Relationship of Anterior Cruciate Ligament Volume and T2* Relaxation Time to Anterior Knee Laxity.Orthopaedic journal of sports medicine · 2021Article
- Musculoskeletal Changes Across the Lifespan: Nutrition and the Life-Course Approach to Prevention.Frontiers in medicine · 2021Review
- Impact of HIV-1 Infection and Antiretroviral Therapy on Bone Homeostasis and Mineral Density in Vertically Infected Patients.Journal of osteoporosis · 2019Article
- Age estimation in competitive sports.International journal of legal medicine · 2017Review
- Predictors of Bone Mineral Density among Asian Indians in Northern Mississippi: A Pilot Study.Journal of research in health sciences · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Although primarily considered a disorder of the elderly, emerging evidence suggests the antecedents of osteoporosis are established during childhood and adolescence. A complex interplay of genetic, environmental, hormonal and behavioral factors determines skeletal development, and a greater effort is needed to identify the most critical factors that establish peak bone strength. Indeed, knowledge of modifiable factors that determine skeletal development may permit optimization of skeletal health during growth and could potentially offset reductions in bone strength with aging. The peripubertal years represent a unique period when the skeleton is particularly responsive to loading exercises, and there is now overwhelming evidence that exercise can optimize skeletal development. While this is not controversial, the most effective exercise prescription and how much investment in this prescription is needed to significantly impact bone health continues to be debated. Despite considerable progress, these issues are not easy to address, and important questions remain unresolved. This review focuses on the key determinants of skeletal development, whether exercise during childhood and adolescence should be advocated as a safe and effective strategy for optimizing peak bone strength, and whether investment in exercise early in life protects against the development of osteoporosis and fractures later in life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.